Study seeks to predict which teens benefit from brain stimulation and therapy

NCT ID NCT07283419

Completed Knowledge-focused Sponsor: The First Hospital of Hebei Medical University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 163 teens with major depression to see if family factors (like conflict or closeness) and cognitive skills (like attention and planning) could predict how well they respond to a combination of repetitive transcranial magnetic stimulation (rTMS) and group cognitive behavioral therapy. The goal was to identify early clues that might help personalize treatment. The study is complete and focused on gathering knowledge, not testing a new cure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: repetitive transcranial magnetic stimulation (rTMS) and group cognitive behavioral therapy
What this could lead to: If successful, this could help doctors personalize depression treatment for teens by identifying who will benefit most from combining rTMS with group therapy.
What could go wrong: This is a completed observational study, not a treatment trial, so it won't prove the therapy works—only which factors might predict response. Results may not apply to all teens with depression.

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Conditions

The condition(s) this trial relates to.

major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADOLESCENT DEPRESSION MAJOR DEPRESSIVE DISORDER (MDD)

Contacts and locations

Locations

The First Hospital of Hebei Medical University

Shijiazhuang, Hebei, 050000, China

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