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Gentle brain zaps may boost speech recovery after stroke

NCT ID NCT07700537

Symptom relief Sponsor: The First Affiliated Hospital of Anhui Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 14, 2026 · Last updated Jul 17, 2026 · Updated 2 times

Summary

This study tests whether a gentle, non-invasive brain stimulation technique called tDCS can help people recover language abilities after a stroke that causes aphasia. Participants receive 14 sessions of tDCS over 7 days combined with speech therapy. Researchers measure language improvements and use brain scans to understand how the stimulation works.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial direct current stimulation (tDCS), a non-invasive brain stimulation technique that applies a weak direct current to the scalp to regulate neuronal activity
What this could lead to
If effective, tDCS could become a safe, low-cost add-on to speech therapy for people recovering language after a stroke.
What could go wrong
This is a small, early-stage study with only 40 participants, so results may not apply broadly. The benefit over speech therapy alone is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2025

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients must be between 18 and 80 years of age * First stroke in the left hemisphere * Stroke onset within the past 12 weeks * Native Chinese speakers who were able to communicate normally prior to onset * Diagnosed with aphasia using the ABC scale * Right-handed * Informed consent obtained from the patient and family members Exclusion Criteria: * Time since stroke onset exceeds 12 weeks * History of psychiatric or neurological disorders * History of surgery for severe head trauma, brain tumors, or brain abscesses * Severe articulation disorders * Claustrophobia or implants incompatible with MRI * Inability to cooperate with language scale testing or fMRI scanning * History of previous stroke

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Conditions

The condition(s) this trial relates to.

aphasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Post-stroke aphasia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • transcranial direct current stimulation (tDCS)

    RECRUITING

    Hefei, Anhui, China

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