A brain zap may curb chemsex cravings: trial puts tDCS to the test

NCT ID NCT05945199

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 02, 2026 · Last updated Sep 03, 2026 · Updated 1 time

Summary

This trial tests whether a gentle brain stimulation technique called tDCS can lower the craving for chemsex, the use of drugs to enhance sexual experiences. Researchers will give 40 adults either real or sham stimulation for five days, then track their urges and risk behaviors for 12 weeks. The goal is to see if this approach can help people who want to cut back or stop, since no proven treatment exists yet.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial direct current stimulation (tDCS), a non-invasive brain stimulation device
What this could lead to
If it works, this could offer a first treatment to help people reduce or stop chemsex, lowering their risk of infections, addiction, and overdose.
What could go wrong
This is a small pilot study with only 40 participants, so results may not apply broadly. The effect on craving may be short-lived or no better than sham stimulation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2024

Expected to finish

Oct 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient who provides written consent * Patient aged ≥ 18 years * Patient motivated and willing to change chemsex behavior, assessed by examiner during screening and inclusion visits * Patient using at least one of the following psychoactive substances to modify sexual performance and/or experience: * Cathinones, or methamphetamine, or MDMA, or cocaine, or ketamine, or GBL/GHB * ≥ 1 time per month over the past 6 months and/or ≥ 10 times over the past year Exclusion Criteria: * Patient with a substance use disorder not involved in the practice of chemsex * Patient with a recent change (\< 1 month) in the prescription of a psychotropic treatment * Patient presenting an acute psychiatric condition requiring hospitalization and/or immediate modification of a psychotropic treatment * Patients with unstable or uncontrolled neuropsychiatric disease * Patients with a history of epileptic seizures * Patients with unexplained episodes of loss of consciousness, as this condition may be linked to cerebral alterations or epilepsy * Patients with advanced or decompensated somatic pathology, requiring hospitalization expected during study follow-up * Patients suffering from any serious life-threatening illness, such as congestive heart failure, chronic obstructive pulmonary disease or active neoplasia * Patients with implanted cerebral medical devices, implanted pacemakers, or any electrically, magnetically or mechanically activated implant. * Patients with cardiac, neural or drug implants * Patients with vascular clips or other electrically sensitive support systems in the brain * Patients with severe brain lesions * Patients with skin lesions at stimulation sites * Patients with skin problems such as dermatitis, psoriasis or eczema * Patients with severe or frequent headaches * Patients who have already benefited from tDCS sessions * Pregnant, parturient or breast-feeding women (pregnancy test) * Staff working in the addictology department of Dijon University Hospital * Patient participating in another clinical trial * Patient not affiliated to national health insurance * Patient unable to complete assessment scales * Patient under psychiatric care without consent or under legal protection (guardianship, curatorship) * Major incapable or unable to provide consent

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Conditions

The condition(s) this trial relates to.

Chemsex

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • CHU Dijon Bourgogne

    RECRUITING

    Dijon, France

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