Ancient herbs take on radiation mouth pain: new trial launches

NCT ID NCT07282483

Recruiting now Symptom relief Sponsor: West China Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial tests whether a traditional Chinese medicine oral liquid and mouthwash can prevent or reduce severe mouth sores caused by radiation therapy in head and neck cancer patients. About 118 adults aged 18-65 will receive either the herbal treatment or a placebo alongside their standard radiation. The main goal is to see if fewer people develop painful, grade 3 or higher mucositis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Qingying oral liquid and modified Da Huang-Huang Lian Xiexin mouthwash (traditional Chinese medicine)
What this could lead to: If it works, this could offer a natural option to reduce severe mouth pain during radiation, helping patients eat and speak more comfortably.
What could go wrong: This is a small, early-phase trial with only 118 people, so results may not apply widely. The placebo group also gets a fake treatment, so any benefit might be small or due to chance.

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Conditions

The condition(s) this trial relates to.

chemotherapy-induced oral mucositis head and neck cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RADIATION INDUCED ORAL MUCOSITIS

Contacts and locations

Locations

West China Hospital
RECRUITING

Chengdu, Sichuan, 610041, China

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