Ancient herbs take on radiation mouth pain: new trial launches

NCT ID NCT07282483

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial tests whether a traditional Chinese medicine oral liquid and mouthwash can prevent or reduce severe mouth sores caused by radiation therapy in head and neck cancer patients. About 118 adults aged 18-65 will receive either the herbal treatment or a placebo alongside their standard radiation. The main goal is to see if fewer people develop painful, grade 3 or higher mucositis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Qingying oral liquid and modified Da Huang-Huang Lian Xiexin mouthwash (traditional Chinese medicine)

What this could lead to

If it works, this could offer a natural option to reduce severe mouth pain during radiation, helping patients eat and speak more comfortably.

What could go wrong

This is a small, early-phase trial with only 118 people, so results may not apply widely. The placebo group also gets a fake treatment, so any benefit might be small or due to chance.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chemotherapy-induced oral mucositis head and neck cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • West China Hospital

    RECRUITING

    Chengdu, Sichuan, 610041, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••