Alzheimer's drug TB006 safety study halted early
NCT ID NCT05476783
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at the long-term safety of an experimental drug called TB006 (oloctinebart) in people with Alzheimer's disease. It included 119 participants who had either completed a previous TB006 study or were new to the drug. The study was terminated early, so the full safety and effectiveness data are not available.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
TB006 (oloctinebart)
What this could lead to
If successful, this could point toward a treatment that slows Alzheimer's progression.
What could go wrong
The study was terminated early, so we don't have complete safety or effectiveness data. It was also a small, open-label extension study, which limits what we can conclude.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Clinical Trial Site
San Diego, California, 92103, United States
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Clinical Trial Site
Delray Beach, Florida, 33445, United States
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Clinical Trial Site
Lady Lake, Florida, 32159, United States
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Clinical Trial Site
Maitland, Florida, 32751, United States
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Clinical Trial Site
Miami, Florida, 33135, United States
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Clinical Trial Site
Miami, Florida, 33137, United States
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Clinical Trial Site
Miami, Florida, 33165, United States
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Clinical Trial Site
West Palm Beach, Florida, 33407, United States
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Clinical Trial Site
Winter Park, Florida, 32789, United States
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Clinical Trial Site
Winter Park, Florida, 32792, United States
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Clinical Trial Site
Decatur, Georgia, 30030, United States
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Clinical Trial Site
Matthews, North Carolina, 28105, United States
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Clinical Trial Site
Fairfax, Virginia, 22031, United States