Alzheimer's drug TB006 safety study halted early

NCT ID NCT05476783

Terminated Disease control Sponsor: TrueBinding, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at the long-term safety of an experimental drug called TB006 (oloctinebart) in people with Alzheimer's disease. It included 119 participants who had either completed a previous TB006 study or were new to the drug. The study was terminated early, so the full safety and effectiveness data are not available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: TB006 (oloctinebart)
What this could lead to: If successful, this could point toward a treatment that slows Alzheimer's progression.
What could go wrong: The study was terminated early, so we don't have complete safety or effectiveness data. It was also a small, open-label extension study, which limits what we can conclude.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER'S DISEASE

Contacts and locations

Locations

Clinical Trial Site

San Diego, California, 92103, United States
Clinical Trial Site

Delray Beach, Florida, 33445, United States
Clinical Trial Site

Lady Lake, Florida, 32159, United States
Clinical Trial Site

Maitland, Florida, 32751, United States
Clinical Trial Site

Miami, Florida, 33135, United States
Clinical Trial Site

Miami, Florida, 33137, United States
Clinical Trial Site

Miami, Florida, 33165, United States
Clinical Trial Site

West Palm Beach, Florida, 33407, United States
Clinical Trial Site

Winter Park, Florida, 32789, United States
Clinical Trial Site

Winter Park, Florida, 32792, United States
Clinical Trial Site

Decatur, Georgia, 30030, United States
Clinical Trial Site

Matthews, North Carolina, 28105, United States
Clinical Trial Site

Fairfax, Virginia, 22031, United States

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