Can TAVI be done safely without a surgery team on standby?
NCT ID NCT05751577
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether a heart valve replacement procedure called TAVI can be safely performed in hospitals that do not have on-site cardiac surgery backup. It involves 657 patients with severe aortic stenosis who are at high risk for surgery. The same experienced doctors perform TAVI in both types of hospitals, and the study compares rates of death, stroke, and hospital readmission over one year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could show that TAVI can be safely performed in centers without on-site cardiac surgery, expanding access to this procedure for more patients.
What could go wrong
This is a non-inferiority trial, not testing a new treatment. Results may not apply to less experienced teams or different patient populations. Emergent complications requiring surgery remain a risk.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Azienda Ospedaliera di Reggio Emilia
Reggio Emilia, Italy
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Azienda Ospedaliero Universitaria di Ferrara
Ferrara, Italy
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Azienda ULSS 3 Serenissima, Ospedale di Mirano
Mirano, Italy
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Azienda Unità Sanitaria Locale
Bologna, Bologna, 40100, Italy
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Ospedale "Morgagni - Pierantoni" di Forlì
Forlì, Italy
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Ospedale Cardinal Massaia di Asti
Asti, Italy
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Ospedale Civile di Baggiovara
Modena, Italy
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Ospedale Civile di Venezia SS Giovanni e Paolo
Venezia, Italy
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Ospedale Guglielmo da Saliceto di Piacenza
Piacenza, Italy
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Ospedale Infermi di Rimini
Rimini, Italy
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Ospedale Misericordia di Grosseto
Grosseto, Italy
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Ospedale San Donato di Arezzo
Arezzo, Italy
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Ospedale Santa Maria delle Croci
Ravenna, Italy
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Ospedale degli Infermi di Biella
Biella, Italy