New blood thinner combo may be safer after valve replacement

NCT ID NCT02817789

First seen May 14, 2026 · Last updated May 15, 2026 · Updated 1 time

Summary

This study tested whether a single blood thinner (ticagrelor) is safer than the standard two-drug combination after a minimally invasive heart valve replacement (TAVI) for aortic stenosis. 50 older adults participated, and researchers tracked complications like bleeding, stroke, and kidney injury within 30 days. The goal was to find the best anti-clotting approach to reduce risks after the procedure.

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Contacts and locations

Locations

  • APHM

    Marseille, 13005, France

  • APHP

    Paris, 75013, France

  • CHRU de Lille

    Lille, 59037, France

  • CHRU de Nîmes

    Nîmes, 30029, France

  • CHU de Bordeaux

    Pessac, 33604, France

Conditions

Explore the condition pages connected to this study.