Lung cancer combo trial halted after just 5 patients
NCT ID NCT05313009
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a combination of two targeted drugs, tarloxotinib and sotorasib, in people with advanced non-small cell lung cancer that has a specific genetic change called KRAS G12C. Participants had already tried other treatments, including a KRAS-targeting drug, and their cancer had gotten worse. The trial was stopped early after enrolling only 5 people, so we don't have clear results on how well the combination works.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hollings Cancer Center at Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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Other studies related to the condition(s) this trial covers.
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