Lung cancer combo trial halted after just 5 patients
NCT ID NCT05313009
First seen Jan 06, 2026 · Last updated Apr 24, 2026 · Updated 17 times
Summary
This study tested a combination of two drugs, tarloxotinib and sotorasib, in people with advanced non-small cell lung cancer that has a specific genetic change called KRAS G12C. Participants had already tried other treatments, including a KRAS-targeting drug, but their cancer continued to grow. The trial was stopped early after enrolling only 5 people, so we do not have enough information to know if the combination works or is safe.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Hollings Cancer Center at Medical University of South Carolina
Charleston, South Carolina, 29425, United States
Conditions
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