New Two-Pronged attack on tough prostate cancers before surgery

NCT ID NCT05593497

Summary

This study is testing whether a new drug, capivasertib, combined with standard hormone-blocking drugs, can shrink aggressive prostate tumors before surgery. It is for men with high-risk prostate cancer that has a specific genetic feature (PTEN loss) linked to treatment resistance. The goal is to see if this pre-surgery treatment leaves little to no cancer behind, potentially leading to better long-term outcomes.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • James J. Peters VA Medical Center, Bronx, NY

    RECRUITING

    The Bronx, New York, 10468-3904, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • Ralph H. Johnson VA Medical Center, Charleston, SC

    RECRUITING

    Charleston, South Carolina, 29401-5703, United States

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-••••

  • South Texas Health Care System, San Antonio, TX

    TERMINATED

    San Antonio, Texas, 78229-4404, United States

  • VA Greater Los Angeles Healthcare System, West Los Angeles, CA

    RECRUITING

    West Los Angeles, California, 90073-1003, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • VA Portland Health Care System, Portland, OR

    RECRUITING

    Portland, Oregon, 97207-2964, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • VA Puget Sound Health Care System Seattle Division, Seattle, WA

    RECRUITING

    Seattle, Washington, 98108-1532, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.