New Alpha-Particle therapy targets tough melanoma
NCT ID NCT05655312
First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 23 times
Summary
This study tests a new treatment called [212Pb]VMT01 for people with advanced melanoma that has not responded to prior therapies. The treatment delivers a powerful alpha-particle radiation directly to melanoma cells. It is given alone or with the immunotherapy drug nivolumab. The goal is to find safe doses and see if it shrinks tumors.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Locations
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Fox Chase Cancer Center
RECRUITINGPhiladelphia, Pennsylvania, 19111, United States
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Mayo Clinic
RECRUITINGJacksonville, Florida, 32224, United States
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Mayo Clinic Rochester
RECRUITINGRochester, Minnesota, 55905, United States
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Nebraska Cancer Specialists
RECRUITINGOmaha, Nebraska, 68130, United States
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Saint Louis University Hospital
RECRUITINGSt Louis, Missouri, 63110, United States
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Sarasota Memorial Hospital
RECRUITINGSarasota, Florida, 34239, United States
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UPMC Hillman Cancer Center
RECRUITINGPittsburgh, Pennsylvania, 15232, United States
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University of California Irvine
RECRUITINGOrange, California, 92868, United States
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University of Iowa
RECRUITINGIowa City, Iowa, 52242, United States
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University of Kentucky
RECRUITINGLexington, Kentucky, 40536, United States
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University of Miami
RECRUITINGMiami, Florida, 33136, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Wisconsin Carbone Cancer Center
RECRUITINGMadison, Wisconsin, 53792, United States
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Washington University of St. Louis
RECRUITINGSt Louis, Missouri, 63110, United States
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Conditions
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