Three-Drug showdown aims to end stent pain for kidney stone patients

NCT ID NCT06803030

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study compares three common drugs—tamsulosin, solifenacin, and mirabegron—to see which one works best for reducing symptoms caused by ureteral stents placed after kidney stone surgery. About 189 adults will take one of the three pills daily and report their symptoms using a questionnaire. The goal is to find the most effective option to improve comfort while the stent is in place.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tamsulosin, solifenacin, mirabegron

What this could lead to

If successful, this could identify the best drug to reduce pain and urinary symptoms caused by ureteral stents, improving comfort for patients after stone surgery.

What could go wrong

This is a moderate-sized Phase 3 trial, but results may not apply to all stent patients. The drugs have known side effects like dry mouth or dizziness, and the best option may still leave some symptoms.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

urolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • NAMS, Bir Hospital

    RECRUITING

    Kathmandu, Bagmati, 44600, Nepal

    Contact Phone: •••-•••-•••• Email: •••••@•••••