New hope for Hard-to-Treat prostate cancer: drug combo trial launches

NCT ID NCT06844383

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 27 times

Summary

This study tests whether the drug talazoparib, given alone or with enzalutamide, can slow cancer growth in men with a specific type of advanced prostate cancer (metastatic castration-resistant) that has certain gene mutations (HRR) and has already progressed after treatment with abiraterone. About 126 participants will be randomly assigned to one of two treatment groups. The goal is to see which approach delays cancer progression longer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dana Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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