New hope for advanced breast cancer: targeted drug combo under study

NCT ID NCT03959891

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 27 times

Summary

This early-phase study tests whether adding an AKT inhibitor (ipatasertib) to standard hormone therapy, with or without a CDK 4/6 inhibitor, is safe and can shrink tumors in women with metastatic hormone receptor-positive breast cancer. About 77 participants will receive the combination to see how well it controls the disease. The goal is to manage the cancer, not cure it.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BREAST CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Massachusetts General Hospital Cancer Center

    Boston, Massachusetts, 02115, United States

Conditions

Explore the condition pages connected to this study.