New drug shows promise for rare liver disease in kids

NCT ID NCT05543174

First seen Jan 31, 2026 · Last updated May 21, 2026 · Updated 14 times

Summary

This study tested a drug called TAK-625 in 7 Japanese children with Alagille Syndrome, a rare liver disease. The goal was to see if the drug could lower bile acid levels and reduce severe itching. Participants took the drug for up to 34 months and had regular clinic visits. Results will help determine the right dose for future use.

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Contacts and locations

Locations

  • Juntendo University Hospital

    Bunkyo-ku, Tokyo, Japan

  • Kindai University Nara Hospital

    Ikoma, Nara, Japan

  • Kyoto University Hospital

    Kyoto, Japan

  • Miyagi Children's Hospital

    Sendai, Miyagi, Japan

  • Osaka University Hospital

    Suita, Osaka, Japan

  • Saitama Prefectural Children's Medical Center

    Saitama, Japan

  • University of Tsukuba Hospital

    Tsukuba, Ibaraki, Japan

  • Yokohamashi Tobu Hospital

    Yokohama, Kanagawa, Japan

Conditions

Explore the condition pages connected to this study.