Promising combo targets rare blood cancer in early trial

NCT ID NCT07007052

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study tests a two-drug combination (tagraxofusp and venetoclax) in adults with a rare and aggressive blood cancer called BPDCN who have not had prior treatment. The main goal is to see if the combination can achieve complete remission after 3 months. Depending on results, patients may continue treatment, receive a stem cell transplant, or stop therapy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Blastic Plasmacytoid Dendritic Cell Neoplasm CD4+/CD56+ hematodermic neoplasm Pathologic Complete Response

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AMIENS - CH Amiens Picardie Site Sud

    RECRUITING

    Amiens, 80054, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • ANGERS - CHU - Maladies du sang

    RECRUITING

    Angers, 49933, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • AP-HP - Hôpital Necker

    NOT_YET_RECRUITING

    Paris, 75015, France

    Contact Email: •••••@•••••

  • AP-HP- CRETEIL - CHU Henri Mondor

    RECRUITING

    Créteil, 94000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • APHP - HOPITAL COCHIN - Hématologie

    NOT_YET_RECRUITING

    Paris, 75014, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • APHP - Hôpital Saint-Louis - Hématologie adultes

    NOT_YET_RECRUITING

    Paris, 75010, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • ARGENTEUIL - Centre hospitalier Victor Dupouy

    NOT_YET_RECRUITING

    Argenteuil, France

    Contact Email: •••••@•••••

  • AVIGNON - Centre Hospitalier

    NOT_YET_RECRUITING

    Avignon, 84000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • BESANCON - Hôpital Jean Minjoz - Hématologie

    RECRUITING

    Besançon, 25030, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • BORDEAUX - Hôpital Haut-Levêque

    RECRUITING

    Pessac, 33600, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU SAINT-ETIENNE - iCHUSE

    NOT_YET_RECRUITING

    Saint-Etienne, 42271, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CLAMART - Hôpital d'Instruction des Armées de Percy

    NOT_YET_RECRUITING

    Clamart, 92140, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Clermont-Ferrand - Chu Estaing

    NOT_YET_RECRUITING

    Clermont-Ferrand, 63000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Corbeil-Essonnes - Ch Sud Francilien

    NOT_YET_RECRUITING

    Corbeil-Essonnes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Grenoble CHU - Hématologie Clinique

    NOT_YET_RECRUITING

    Grenoble, 38043, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • LILLE CHU - Hôpital Claude Huriez

    RECRUITING

    Lille, 59037, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • LYON HCL- Site Sud

    RECRUITING

    Lyon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Limoges CHU

    NOT_YET_RECRUITING

    Limoges, France

    Contact Email: •••••@•••••

  • MARSEILLE - Institut Paoli-Calmettes

    NOT_YET_RECRUITING

    Marseille, 13000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • METZ - CHR Metz-Thionville

    NOT_YET_RECRUITING

    Metz, 57085, France

    Contact Email: •••••@•••••

  • MULHOUSE GHRMSA - Hôpital E. Muller - Hématologie

    NOT_YET_RECRUITING

    Mulhouse, 68070, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Montpellier - Chu Saint Eloi

    NOT_YET_RECRUITING

    Montpellier, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NANCY - CHU de Brabois

    NOT_YET_RECRUITING

    Vandœuvre-lès-Nancy, 54500, France

    Contact Email: •••••@•••••

  • NANTES - Hôpital Hôtel Dieu - Hématologie Clinique

    NOT_YET_RECRUITING

    Nantes, 44093, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nimes CHU

    NOT_YET_RECRUITING

    Nîmes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • POITIERS - Hôpital La Milétrie - Hématologie Clinique

    NOT_YET_RECRUITING

    Poitiers, 86000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • REIMS - Hôpital Robert Debré - Hématologie Clinique

    NOT_YET_RECRUITING

    Reims, 51100, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • RENNES - CHU Pontchaillou - Hématologie Clinique

    NOT_YET_RECRUITING

    Rennes, 35033, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • ROUEN - Centre Henri Becquerel - Service Hématologie Clinique

    RECRUITING

    Rouen, 76038, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Strasbourg - Institut de Cancerologie Strasbourg

    NOT_YET_RECRUITING

    Strasbourg, 67200, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • TOURS - Hôpital Bretonneau

    NOT_YET_RECRUITING

    Tours, 37000, France

    Contact Email: •••••@•••••

  • Toulouse - IUCT Oncopole - Service d'Hématologie

    NOT_YET_RECRUITING

    Toulouse, France

    Contact Email: •••••@•••••

  • VERSAILLES - Hôpital André Mignot

    NOT_YET_RECRUITING

    Versailles, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Villejuif Igr - Gustave Roussy

    NOT_YET_RECRUITING

    Villejuif, 94804, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••