Could a common ED drug boost chemo for stomach cancer?

NCT ID NCT05709574

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 29 times

Summary

This study tests whether adding tadalafil (a drug for erectile dysfunction) to standard chemotherapy can help shrink stomach or gastroesophageal junction tumors before surgery. Ten adults with resectable cancer will take tadalafil alone for two weeks, then combined with chemo for about eight weeks. The goal is to see if this approach is safe and reduces immune cells that block the body's ability to fight cancer.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Arizona Cancer Center at UMC North/University Medical Center

    RECRUITING

    Tucson, Arizona, 85719, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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