Experimental cell therapy offers hope for transplant patients with rare Virus-Driven cancer

NCT ID NCT03394365

Recruiting now Disease control Sponsor: Pierre Fabre Medicament Source: ClinicalTrials.gov ↗

Summary

This study is testing an experimental cell therapy called tabelecleucel for transplant patients who develop a rare cancer caused by Epstein-Barr virus. The treatment uses specially prepared immune cells to target and fight the virus-related cancer in patients who haven't responded to standard medications. Researchers will give these cells through IV infusions and monitor patients for up to 5 years to see how well the treatment works and how safe it is.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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Locations

Alberta Children's Hospital (Adults and Pediatrics)
RECRUITING

Calgary, Alberta, T3B 6A8, Canada

Contact Phone: •••-•••-••••
Ann & Robert H. Lurie Children's Hospital of Chicago (Adults and Pediatrics)
RECRUITING

Chicago, Illinois, 60611, United States

Contact Phone: •••-•••-••••
Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (Adults and Pediatrics)
RECRUITING

Columbus, Ohio, 43210, United States

Contact Phone: •••-•••-••••
Arthur M. Blank Hospital (Pediatrics)
RECRUITING

Atlanta, Georgia, 30329, United States

Contact Phone: •••-•••-••••
Azienda Ospedaliera - Universitaria Città della Salute e della Scienza di Torino (Adults only)
COMPLETED

Torino, Torino, 10126, Italy
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda (Adults only)
COMPLETED

Milan, Milano, 20162, Italy
Baylor Scott and White Research Institute (Adults only)
RECRUITING

Dallas, Texas, 75246, United States

Contact Phone: •••-•••-••••
Carolinas Medical Center/Levine Children's Hospital (Adults and Pediatrics)
RECRUITING

Charlotte, North Carolina, 28204, United States

Contact Phone: •••-•••-••••
Centre Hospitalier Régional Universitaire de Lille (Adults and Pediatrics)
COMPLETED

Lille, Hauts-de-France, 59037, France
Centre Hospitalier Universitaire de Bordeaux (Adults only)
COMPLETED

Pessac, Aquitaine, 33600, France
Centre Hospitalier Universitaire de Liège Site Sart Tilman (Adults and Pediatrics)
COMPLETED

Liège, Brussels Capital, 4000, Belgium
Children's Hospital Los Angeles, Div. of Research Immunology/BMT (Adults and Pediatrics)
RECRUITING

Los Angeles, California, 90027, United States

Contact Phone: •••-•••-••••

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City of Hope (Adults and Pediatrics)
COMPLETED

Duarte, California, 91010, United States
Cleveland Clinic Foundation (Adults and Pediatrics)
RECRUITING

Cleveland, Ohio, 44195, United States

Contact Phone: •••-•••-••••
Columbia University Medical Center (Adults and Pediatrics)
COMPLETED

New York, New York, 10032, United States
Dana Farber Cancer Institute, Brigham and Women's Hospital (Adults and Pediatrics)
RECRUITING

Boston, Massachusetts, 02215, United States

Contact Phone: •••-•••-••••
Duke Cancer Institute (Adults and Pediatrics)
RECRUITING

Durham, North Carolina, 27710, United States

Contact Phone: •••-•••-••••
Fiona Stanley Hospital (Adults only)
RECRUITING

Murdoch, Western Australia, 6150, Australia

Contact Phone: •••-•••-••••
Fondazione IRCCS Policlinico San Matteo (Adults and Pediatrics)
COMPLETED

Pavia, Pavia, 27100, Italy
Fondazione Policlinico Universitario Agostino Gemelli (Adults only)
COMPLETED

Roma, Roma, 00168, Italy
Froedtert and Medical College of Wisconsin - Clinical Cancer Center (Adults only)
COMPLETED

Milwaukee, Wisconsin, 53226, United States
Hospital Duran i Reynals (Adults and Pediatrics)
RECRUITING

Badalona, BARCELONA, 8908, Spain

Contact Phone: •••-•••-••••
Hospital General Universitario Gregorio Marañón (Adults and Pediatrics)
RECRUITING

Madrid, Madrid, 28009, Spain

Contact Phone: •••-•••-••••
Hospital Universitari Vall d'Hebrón - Institut de Recerca (Adults and Pediatrics)
SUSPENDED

Barcelona, Barcelona, 08035, Spain
Hospital Universitario La Fe (Adults and Pediatrics)
RECRUITING

Valencia, Valencia, 46009, Spain

Contact Phone: •••-•••-••••
Hospital Universitario Marqués de Valdecilla (Adults and Pediatrics)
RECRUITING

Santander, Cantabria, 39008, Spain

Contact Phone: •••-•••-••••
Hospital of the University of Pennsylvania (Adults only)
RECRUITING

Philadelphia, Pennsylvania, 19104, United States

Contact Phone: •••-•••-••••
Hôpital Necker-Enfants Malades (Pediatrics only)
COMPLETED

Paris, Île-de-France Region, 75015, France
Hôpital Saint Antoine (Adults only)
COMPLETED

Paris, Île-de-France Region, 75571, France
Hôpital Universitaire Pitié Salpêtrière (Adults only)
COMPLETED

Paris, Île-de-France Region, 75651, France
Imperial College Healthcare NHS Trust (Adults only)
RECRUITING

London, England, W12 0HS, United Kingdom

Contact Phone: •••-•••-••••
King's College Hospital NHS Foundation Trust (Adults only)
COMPLETED

London, England, SE5 9RS, United Kingdom
Loma Linda University Medical Center (Adults only)
RECRUITING

Loma Linda, California, 92354, United States

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Loyola University Medical Center (Adults and Pediatrics)
RECRUITING

Maywood, Illinois, 60153, United States

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MD Anderson Cancer Center (Pediatrics and Adult)
RECRUITING

Houston, Texas, 77030, United States

Contact Phone: •••-•••-••••
MedStar Georgetown University Hospital (Adults and Pediatrics)
RECRUITING

Washington D.C., District of Columbia, 20007, United States

Contact Phone: •••-•••-••••
Medical University of South Carolina (Adults and Pediatrics)
ACTIVE_NOT_RECRUITING

Charleston, South Carolina, 29425, United States
Medizinische Universitat Wien (Adults only)
ACTIVE_NOT_RECRUITING

Vienna, Austria, 1090, Austria
Memorial Sloan Kettering Cancer Center (Adults and Pediatrics)
COMPLETED

New York, New York, 10065, United States
Montefiore Medical Center (Adults only)
COMPLETED

The Bronx, New York, 10467, United States
Montefiore Medical Center (Pediatrics only)
COMPLETED

The Bronx, New York, 10467, United States
Nationwide Children's Hospital (Pediatrics only)
COMPLETED

Columbus, Ohio, 43205, United States
Oregon Health and Science University Physicians Pavilion (Adults and Pediatrics)
RECRUITING

Portland, Oregon, 97239, United States

Contact Phone: •••-•••-••••
Ospedale Pediatrico Bambino Gesu (Pediatrics only)
COMPLETED

Roma, Roma, 165, Italy
Princess Margaret Cancer Centre (Adults only)
RECRUITING

Toronto, Ontario, M5G 2M9, Canada

Contact Phone: •••-•••-••••
Royal Adelaide Hospital (Adults only)
RECRUITING

Adelaide, South Australia, 5000, Australia

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Saint Jude Children's Research Hospital (Pediatrics only)
COMPLETED

Memphis, Tennessee, 38105, United States
Sick Kids (Pediatrics only)
RECRUITING

Toronto, Ontario, M5G 1X8, Canada

Contact Phone: •••-•••-••••
The Children's Hospital at Westmead (Pediatrics only)
RECRUITING

Westmead, New South Wales, 2145, Australia

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The Children's Hospital of Philadelphia Oncology Division, Blood & Marrow Transplant Section (Pediatrics)
RECRUITING

Philadelphia, Pennsylvania, 19104, United States

Contact Phone: •••-•••-••••
The Prince Charles Hospital (Adults only)
RECRUITING

Chermside, Queensland, 4032, Australia

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The Royal Children's Hospital Melbourne (Pediatrics only)
RECRUITING

Melbourne, Victoria, 3052, Australia

Contact Phone: •••-•••-••••
UCLA Medical Center (Adults and Pediatrics)
COMPLETED

Los Angeles, California, 90095, United States
Universitair Ziekenhuis Leuven (Adults and Pediatrics)
ACTIVE_NOT_RECRUITING

Leuven, Flemish Brabant, 3000, Belgium
University Hospital Virgen del Rocio (Adults and Pediatrics)
RECRUITING

Seville, Spain, 41013, Spain

Contact Phone: •••-•••-••••
University Hospitals Birmingham NHS Foundation Trust (Adults only)
RECRUITING

Birmingham, England, B15 2GW, United Kingdom

Contact Phone: •••-•••-••••
University of California Davis Comprehensive Cancer Center (Adults only)
COMPLETED

Sacramento, California, 95817, United States
University of California San Diego Moores Cancer Center (Adults only)
COMPLETED

La Jolla, California, 92093, United States
University of Chicago Medical Center - Duchossois Center for Advanced Medicine (Adults only)
COMPLETED

Chicago, Illinois, 60637, United States
University of Florida (Adults and Pediatrics)
COMPLETED

Gainesville, Florida, 32610, United States
University of Maryland School of Medicine (Adults only)
COMPLETED

Baltimore, Maryland, 21201, United States
University of Miami/Jackson Memorial Hospital (Adults only)
RECRUITING

Miami, Florida, 33136, United States

Contact Phone: •••-•••-••••
University of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer Center (Adults and Pediatrics)
COMPLETED

Chapel Hill, North Carolina, 27599, United States
University of Pittsburgh Medical Center (Adults only)
COMPLETED

Pittsburgh, Pennsylvania, 15232, United States
University of Texas Southwestern Medical Center - Children's Medical Center (Pediatrics only)
RECRUITING

Dallas, Texas, 75390, United States

Contact Phone: •••-•••-••••
Vanderbilt University Medical Center Henry-Joyce Cancer Clinic (Adults and Pediatrics)
RECRUITING

Nashville, Tennessee, 37232, United States

Contact Phone: •••-•••-••••
Washington University School of Medicine (Adults only)
RECRUITING

St Louis, Missouri, 63110, United States

Contact Phone: •••-•••-••••
Weill Cornell Medicine (Adults only)
COMPLETED

New York, New York, 10021, United States
Westmead Hospital (Adults only)
RECRUITING

Westmead, New South Wales, 2145, Australia

Contact Phone: •••-•••-••••
Winship Cancer Institute (Adults only)
COMPLETED

Atlanta, Georgia, 30322, United States
Yale University (Adults and Pediatrics)
COMPLETED

New Haven, Connecticut, 06519, United States

Conditions

Explore the condition pages connected to this study.

ALLOGENEIC HEMATOPOIETIC CELL TRANSPLANT EPSTEIN-BARR VIRUS+ ASSOCIATED POST-TRANSPLANT LYMPHOPROLIFERATIVE DISEASE (EBV+ PTLD) LYMPHOPROLIFERATIVE DISORDERS SOLID ORGAN TRANSPLANT COMPLICATIONS STEM CELL TRANSPLANT COMPLICATIONS