New hope for hard-to-treat lung cancer: targeted drug shows promise

NCT ID NCT05246514

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a drug called trastuzumab deruxtecan (T-DXd) in 72 people with a specific type of advanced lung cancer (HER2-mutant non-small cell lung cancer) that has worsened after at least one prior treatment. The goal is to see if the drug can shrink tumors and how safe it is. Participants receive the drug intravenously and are monitored for response and side effects.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Site

    Baoding, 071000, China

  • Research Site

    Beijing, 100142, China

  • Research Site

    Beijing, 100191, China

  • Research Site

    Changchun, 130000, China

  • Research Site

    Changsha, 410008, China

  • Research Site

    Changsha, 410013, China

  • Research Site

    Chengdu, 610041, China

  • Research Site

    Chongqing, 400030, China

  • Research Site

    Guangzhou, 510080, China

  • Research Site

    Guangzhou, 510515, China

  • Research Site

    Hangzhou, 310020, China

  • Research Site

    Hangzhou, 310022, China

  • Research Site

    Harbin, 150081, China

  • Research Site

    Hefei, 133500, China

  • Research Site

    Hefei, 230601, China

  • Research Site

    Linyi, 276000, China

  • Research Site

    Nanjing, 210029, China

  • Research Site

    Shandong, China

  • Research Site

    Shanghai, 200025, China

  • Research Site

    Shanghai, 200032, China

  • Research Site

    Shenyang, 110042, China

  • Research Site

    Shenzhen, 518020, China

  • Research Site

    Wuhan, 430022, China

  • Research Site

    Wuhan, 430060, China

  • Research Site

    Xi'an, 710061, China

  • Research Site

    Xiamen, 361003, China

  • Research Site

    Yangzhou, 225001, China

  • Research Site

    Zhengzhou, 450000, China

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