New HER2-Targeting drug shows promise in early cancer trial

NCT ID NCT05872295

First seen Nov 01, 2025 · Last updated Jun 10, 2026 · Updated 30 times

Summary

This study tests IKS014, a drug designed to seek out and destroy HER2-positive cancer cells, in people with advanced solid tumors like breast, stomach, and gastroesophageal cancers. The main goals are to find the safest dose and check for early signs of tumor shrinkage. About 165 participants will receive the drug intravenously, and researchers will monitor side effects and how the body processes the treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Alfred Health

    RECRUITING

    Melbourne, Victoria, 3004, Australia

    Contact Phone: •••-•••-••••

    Contact

  • Auckland City Hospital

    RECRUITING

    Auckland, New Zealand

    Contact

  • Concord Repatriation General Hospital Medical Oncology Clinical Trials Unit

    RECRUITING

    Concord, New South Wales, 2139, Australia

    Contact Phone: •••-•••-••••

    Contact

  • Dana Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact

  • Hoag Memorial Hospital Presbyterian

    RECRUITING

    Newport Beach, California, 92663, United States

    Contact

  • Linear Clinical Research

    RECRUITING

    Nedlands, Western Australia, 6009, Australia

    Contact Phone: •••-•••-••••

    Contact

  • Macquarie University

    RECRUITING

    Sydney, New South Wales, 2109, Australia

    Contact

  • National Cancer Centre Singapore

    RECRUITING

    Singapore, Singapore

    Contact

  • Peninsula & South Eastern Haematology and Oncology Group (PSEHOG)

    RECRUITING

    Frankston, Victoria, 3199, Australia

    Contact Phone: •••-•••-••••

    Contact

  • START Dallas - Fort Worth

    RECRUITING

    Fort Worth, Texas, 76104, United States

    Contact

    Contact Email: •••••@•••••

  • Tan Tock Seng Hospital

    RECRUITING

    Singapore, Singapore

    Contact

  • Tennessee Oncology

    RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact

  • Westmead Hospital

    RECRUITING

    Westmead, New South Wales, 2145, Australia

    Contact Phone: •••-•••-••••

    Contact

Conditions

Explore the condition pages connected to this study.