New drug duo aims to keep ovarian cancer at bay longer

NCT ID NCT06819007

Recruiting now Disease control Sponsor: Daiichi Sankyo Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 3 trial tests whether adding trastuzumab deruxtecan (T-DXd) to standard bevacizumab maintenance therapy can delay cancer progression better than bevacizumab alone in people with HER2-expressing advanced ovarian cancer. About 582 adults whose cancer has a specific protein (HER2) will receive either the combination or single drug after initial chemotherapy. The study is currently recruiting.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Carcinoma, Ovarian Epithelial ovarian cancer ovarian carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OVARIAN CANCER

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

AZ Sint-Lucas
RECRUITING

Ghent, Belgium
Aarhus University Hospital
RECRUITING

Aarhus, Denmark
Addenbrooke's Hospital
RECRUITING

Cambridge, United Kingdom
AdventHealth Cancer Institute
RECRUITING

Orlando, Florida, 32804, United States
Affiliated Hospital (Suzhou First People's Hospital)
RECRUITING

Suzhou, China
Aichi Cancer Center Hospital
RECRUITING

Nagoya, Japan
Akademiska Sjukhuset (Uppsala University Hospital)
RECRUITING

Uppsala, 75185, Sweden
Ann B Barshinger Cancer Institute
RECRUITING

Lancaster, Pennsylvania, 17601, United States
Aretaieio Hospital
RECRUITING

Athens, 11528, Greece
Asan Medical Center
RECRUITING

Seoul, South Korea
Avera Medical Group Gynecologic
RECRUITING

Sioux Falls, South Dakota, 57105, United States
Azienda Ospedaliera Per Lemergenza Cannizzaro
RECRUITING

Catania, Italy
Azienda Ospedaliera Universitaria Policlinico Sant'Orsola Malpighi IRCCS
RECRUITING

Bologna, Italy
Azienda Ospedaliera Universitaria Policlinico Umberto
RECRUITING

Roma, 00161, Italy
Azienda Ospedaliero Universitaria Pisana
RECRUITING

Pisa, Italy
Azienda Socio Sanitaria Territoriale Di Monza (Presidio San Gerardo)
RECRUITING

Monza, Italy
BP A Beneficencia Portuguesa de Sao Paulo
RECRUITING

São Paulo, Brazil
Barts Health NHS Trust
RECRUITING

London, United Kingdom
Beijing Cancer Hospital
RECRUITING

Beijing, China
Broward Health Medical Center
RECRUITING

Fort Lauderdale, Florida, 33316, United States
CHA Bundang Medical Center, CHA University
RECRUITING

Seongnam-si, South Korea
CHU Montpellier, Saint Eloi
RECRUITING

Montpellier, France
CHU Saint Etienne
RECRUITING

Saint-Etienne, France
CHU UCL Namur
RECRUITING

Namur, Belgium
CRLCC Eugene Marquis
RECRUITING

Rennes, France
Cancer Institute Hospital of JFCR
RECRUITING

Kōtoku, 135-8550, Japan
Centre Georges Francois Leclerc
RECRUITING

Dijon, France
Centre Leon Berard
RECRUITING

Lyon, France
Centro De Pesquisas Clinica Reichow
RECRUITING

Blumenau, Brazil
Centro Gaucho Integrado de Oncologia, Hematologia, Ensino e Pesquisa Hospital Mae de Deus
RECRUITING

Porto Alegre, Brazil
Ceon Pesquisas
RECRUITING

Santo André, Brazil
Chang Gung Memorial Hospital
RECRUITING

Linkou Taoyuan, Taiwan
Chongqing Cancer Hospital
RECRUITING

Chongqing, China
Clinica Universidad de Navarra (Calle Marquesado de Santa Marta)
RECRUITING

San Blas-Canillejas, Spain
Clinica Universidad de Navarra (MAD)
RECRUITING

Pamplona, Spain
Cliniques Universitaires Saint-LUC
RECRUITING

Woluwe-Saint-Lambert, Belgium
Columbia University
RECRUITING

New York, New York, 10032, United States
Complejo Hospitalario Universitario A Coruna
RECRUITING

A Coruña, Spain
Complex Oncology Center- Plovdiv EOOD
RECRUITING

Plovdiv, Bulgaria
Corewell Health
RECRUITING

Grand Rapids, Michigan, 49503, United States
Dana-Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215, United States
Debreceni Egyetem
RECRUITING

Debrecen, 4032, Hungary
Disney Family Cancer Center
RECRUITING

Burbank, California, 91505, United States
Endeavor Health Evanston Kellogg Cancer Care Center
RECRUITING

Evanston, Illinois, 60201, United States
Fakultni Nemocnice Bulovka
RECRUITING

Prague, Czechia
Fakultni Nemocnice Kralovske Vinohrady
RECRUITING

Prague, Czechia
Fakultni Nemocnice Ostrava
RECRUITING

Ostrava-Poruba, Czechia
Fakultni Nemocnice V Motole
RECRUITING

Prague, Czechia
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
RECRUITING

Roma, Italy
Fudan University Shanghai Cancer Center
RECRUITING

Shanghai Shi, 200032, China
Fujian Cancer Hospital
RECRUITING

Fuzhou, China
Fukushima Medical University Hospital
RECRUITING

Fukushima, 960-1295, Japan
Fundacao Faculdade Regional De Medicina De Sao Jose Do Rio Preto
RECRUITING

Sao Jose Rio, Brazil
Fundação Doutor Amaral Carvalho
RECRUITING

Jaú, Brazil
Gangnam Severance Hospital, Yonsei University Health System
RECRUITING

Seoul, South Korea
General Hospital of Athens Alexandra
RECRUITING

Athens, 11528, Greece
Genesis Care North Shore (Oncology)
RECRUITING

St Leonards, Australia
Genesis Care, Beaumont House
RECRUITING

Oxford, OX4 6LB, United Kingdom
Genesiscare St Andrews Hospital
RECRUITING

Adelaide, Australia
Gral Medical S.R.L
RECRUITING

Bucharest, Romania
Greater Baltimore Medical Center
RECRUITING

Towson, Maryland, 21204, United States
Groupe Sante CHC/Clinique du MontLegia
RECRUITING

Liège, Belgium
Guangxi Medical University Cancer Hopstial
RECRUITING

Nanning, China
Gujarat Cancer & Research Institute
RECRUITING

Ahmedabad, India
Guys Hospital Cancer Centre
RECRUITING

London, SE1 9RT, United Kingdom
HCG Cancer Centre Vadodara
RECRUITING

Vadodara, India
HCG Manavata Cancer Centre
RECRUITING

Nashik, India
HOSPITAL KUALA LUMPUR(HKL) Kuala
RECRUITING

Lumpur, Malaysia
Hainan General Hospital
RECRUITING

Haikou, China
Harbin Medical University - Tumor Hospital
RECRUITING

Haerbing, China
Henan Cancer Hospital
RECRUITING

Zhengzhou, China
Hopital Claude Huriez- CHU Lille
RECRUITING

Lille, France
Hopital Prive Du Confluent
RECRUITING

Nantes, France
Hopital Saint Joseph- Paris
RECRUITING

Paris, France
Hospital Clinic De Barcelona
RECRUITING

Barcelona, Spain
Hospital Clinico Universitario De Valencia
RECRUITING

Valencia, Spain
Hospital Europeen Georges Pompidou
RECRUITING

Paris, France
Hospital Sultan
RECRUITING

Johor Bahru, Malaysia
Hospital Universitari I Politecnic La Fe
RECRUITING

Valencia, Spain
Hospital Universitari Son Espases
RECRUITING

Palma, Spain
Hospital Universitari Vall D'Hebron
RECRUITING

Barcelona, Spain
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, Spain
Hospital Universitario Donostia
RECRUITING

Planta Baja, Spain
Hospital Universitario La Paz
RECRUITING

Madrid, Spain
Hospital Universitario Ramon y Cajal
RECRUITING

Madrid, Spain
Hospital Universitario Reina Sofia
RECRUITING

Córdoba, Spain
Hospital Universitario Virgen De La Arrixaca
RECRUITING

El Palmar, Spain
Hospital Universitario Virgen del Rocio
RECRUITING

Seville, Spain
Hubei Cancer Hospital
RECRUITING

Wuhan, China
Humanitas San Pio X
RECRUITING

Milan, Italy
Hunan Cancer Hospital
RECRUITING

Changsha, 410006, China
Hyogo Cancer Center
RECRUITING

Akashi, 673-8558, Japan
IEO Istituto Europeo Di Oncologia
RECRUITING

Milan, Italy
Icahn School of Medicine at Mount Sinai
RECRUITING

New York, New York, 10029, United States
Icon Cancer Centre Hobart
RECRUITING

Hobart, Australia
Icon Cancer Centre Wesley
RECRUITING

Auchenflower, Australia
Indiana University
RECRUITING

Indianapolis, Indiana, 46202, United States
Institut Bergonie
RECRUITING

Bordeaux, France
Irmandade Da Santa Casa De Misericordia De Porto Alegre
RECRUITING

Porto Alegre, Brazil
Istituto Nazionale Tumori Fondazione G. Pascale
RECRUITING

Naples, Italy
Istituto Nazionale Tumori Regina Elena Irccs
RECRUITING

Roma, Italy
Istituto Tumori Giovanni Paolo II Irccs Ospedale Oncologico Bari
RECRUITING

Bari, Italy
Iwate Medical University Hospital
RECRUITING

Shiwa-Gun, 028-3695, Japan
Jiangxi Maternal and Child Health Hospital
RECRUITING

Nanchang, China
Jupiter Medical Center
RECRUITING

Jupiter, Florida, 33458, United States
Kaohsiung Chang Gung Memorial Hospital
RECRUITING

Kaohsiung City, Taiwan
Karolinska Universitet Ssjukhuset
RECRUITING

Solna, Sweden
Keimyung University Dongsan Hospital
RECRUITING

Daegu, South Korea
Kindai University Hospital
RECRUITING

Osakasayama-shi, Japan
King George Hospital
RECRUITING

Visakhapatnam, India
Kurume University Hospital
RECRUITING

Kurume-shi, Japan
Laura and Isaac Perlmutter Cancer Center at NYU Langone
RECRUITING

New York, New York, 10016, United States
Legacy Medical Group Gynecologic Oncology
RECRUITING

Portland, Oregon, 97210, United States
Liaoning Cancer Hospital & Institute
RECRUITING

Shenyang, China
Liga Norte-Rio-Grandense Contra o Cancer
RECRUITING

Natal, Brazil
MHAT Park Hospital EOOD
RECRUITING

Plovdiv, Bulgaria
MHAT Serdika EOOD
RECRUITING

Sofia, Bulgaria
MacKay Memorial Hospital- Taipei Branch
RECRUITING

Taipei, Taiwan
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States
Mazowiecki Szpital Wojewodzki W Siedlcach SP Zoo
RECRUITING

Siedlce, Poland
Medeuropa SRL
RECRUITING

Bucharest, Romania
Medeuropa SRL
RECRUITING

Oradea, Romania
Medizinische Universitat Innsbruck
RECRUITING

Innsbruck, Austria
Meir Medical Center
RECRUITING

Kfar Saba, Israel
Memorial Healthcare International SRL
RECRUITING

Bucharest, Romania
Metropolitan Hospital
RECRUITING

Neo Faliro, 18547, Greece
Miami Valley Hospital South
RECRUITING

Centerville, Ohio, 45459, United States
Mie University Hospital
RECRUITING

Tsu, 514-8507, Japan
Minnesota Oncology Hematology PA
RECRUITING

Minneapolis, Minnesota, 55404, United States
Mount Sinai Medical Center
RECRUITING

Miami Beach, Florida, 33140, United States
NHO Hokkaido Cancer Center
RECRUITING

Sapporo, 003-0804, Japan
Nancy N. & J.C Lewis Cancer & Research Pavillion- St. Josephs/ Candler Health System
RECRUITING

Savannah, Georgia, 31405, United States
National And Hapodistrian University of Athens (University General Hospital Attikon)
RECRUITING

Athens, 12462, Greece
National Cancer Center
RECRUITING

Goyang-si, South Korea
National Cancer Center Hospital
RECRUITING

Chūōku, 104-0045, Japan
National Cancer Centre Singapore
RECRUITING

Singapore, 168583, Singapore
National Cancer Institute / Institut Kanser Negara
RECRUITING

Putrajaya, Malaysia
National Cancer Institute Nagpur
RECRUITING

Nagpur, India
National Cheng Kung University Hospital
RECRUITING

Tainan, Taiwan
National Taiwan University Hospital
RECRUITING

Taipei, Taiwan
National University Hospital
RECRUITING

Singapore, Singapore
Niigata Cancer Center Hospital
RECRUITING

Niigata, Japan
Nuovo Ospedale Degli Infermi
RECRUITING

Ponderano, Italy
Okayama University Hosptial
RECRUITING

Okayama, 700-8558, Japan
Oncocentro Belo Horizonte
RECRUITING

Belo Horizonte, Brazil
Osaka International Cancer Institute
RECRUITING

Osaka, Japan
Palo Alto Medical Foundation
RECRUITING

Palo Alto, California, 94301, United States
Providence Cancer Center Oncology
RECRUITING

Portland, Oregon, 97213, United States
Rabin Medical Center-Beilinson Campus
RECRUITING

Petah Tikva, Israel
Rigshospitalet
RECRUITING

Copenhagen, 2100, Denmark
Ruby Hall Clinic
RECRUITING

Pune, India
Saitama Medical University International Medical Center
RECRUITING

Hidaka-Shi, 350-1298, Japan
Samsung Medical Center
RECRUITING

Seoul, South Korea
Sarah Cannon Research Institute (Oncology Associates of Oregon PC)
RECRUITING

Nashville, Tennessee, 37203, United States
Sarawak General Hospital
RECRUITING

Kuching, Malaysia
Saroj Gupta Cancer Center and Research Institute SGCC&RI
RECRUITING

Kolkata, India
Scripps Clinic
RECRUITING

La Jolla, California, 92037, United States
Seoul National University Bundang Hospital
RECRUITING

Seongnam-si, South Korea
Seoul National University Hospital
RECRUITING

Seoul, South Korea
Severance Hospital, Yonsei University Health System
RECRUITING

Seoul, South Korea
Shaare Zedek
RECRUITING

Jerusalem, Israel
Shandong Cancer Hospital
RECRUITING

Jinan, China
Shanxi Cancer Hospital
RECRUITING

Taiyuan, China
Sheba Medical Center
RECRUITING

Tel Litwinsky, Israel
Shizuoka Cancer Center
RECRUITING

Sunto-gun, Japan
Sichuan University West China Second University Hospital
RECRUITING

Chengdu, China
Sjællands Universitet Hospital
RECRUITING

Roskilde, Denmark
Skanes Universitetssjukhus Lund
RECRUITING

Lund, Sweden
St Luke's Hospital
RECRUITING

Thessaloniki, 55236, Greece
St. Lukes University Health Network
RECRUITING

Bethlehem, Pennsylvania, 18015, United States
St. Vincent Gynecologic Oncology
RECRUITING

Billings, Montana, 59102, United States
Sun Yat-Sen University Cancer Center
RECRUITING

Guangzhou, China
Taichung Veterans General Hospital
RECRUITING

Taichung, Taiwan
Taipei Veterans General Hospital
RECRUITING

Taipei, Taiwan
Tata Memorial Hospital
RECRUITING

Mumbai, 400012, India
Tel Aviv Sourasky Medical Center
RECRUITING

Tel Aviv, Israel
The Catholic University of Korea, Seoul St. Mary'S Hospital
RECRUITING

Seoul, South Korea
The Christie Hospital
RECRUITING

Manchester, United Kingdom
The First Affiliated Hospital of Xi'an Jiaotong University
RECRUITING

Xi'an, China
The First Hospital of Jilin University
RECRUITING

Changchun, China
The Lady Davis Carmel Medical Center
RECRUITING

Haifa, Israel
The Second Hospital of Dalian Medical University
RECRUITING

Dalian, China
Tianjin Medical University Cancer Institute & Hospital
RECRUITING

Tianjin, China
Tongji Hospital Tongji Medical College of HUST
RECRUITING

Wuhan, China
Townsville University Hospital Cancer Centre
RECRUITING

Townsville, 4814, Australia
Trials365 LLC
RECRUITING

Shreveport, Louisiana, 71103, United States
Trinity Health St. Joseph Mercy Ann Arbor
RECRUITING

Ann Arbor, Michigan, 48106, United States
UMHAT Sofiamed EOOD
RECRUITING

Sofia, Bulgaria
UMHAT Tsaritsa Yoanna ISUL EAD
RECRUITING

Sofia, Bulgaria
UNC Hospital
RECRUITING

Chapel Hill, North Carolina, 27599, United States
UZ Leuven
RECRUITING

Leuven, Belgium
Uniwersytecki Szpital Kliniczny w Poznaniu
RECRUITING

Poznan, 61848, Poland
Ushato Prof Ivan Chernozemski Ead
RECRUITING

Sofia, Bulgaria
Utah Cancer Specialists Network
RECRUITING

Salt Lake City, Utah, 84106, United States
Valley Health System
RECRUITING

Paramus, New Jersey, 07652, United States
Vseobecna Fakultni Nemocnice V Praze
RECRUITING

Prague, Czechia
Westmead Hospital
RECRUITING

Sydney, Australia
Weston Park Hospital
RECRUITING

Sheffield, S10 2SB, United Kingdom
Woman's Care FL
RECRUITING

St. Petersburg, Florida, 33713, United States
Women's Hospital School of Medicine Zhejiang University
RECRUITING

Hangzhoushi, China
Yamagata University Hospital
RECRUITING

Yamagata, 990-9585, Japan
Yantai Yuhuangding Hospital
RECRUITING

Yantai, China
Yunnan Cancer Hospital
RECRUITING

Kunming, China
Zhejiang Cancer Hospital
RECRUITING

Hangzhou, China
Zhong Da Hospital, Southeast University
RECRUITING

Nanjing, China