New drug combo aims to wipe out breast cancer before surgery
NCT ID NCT02326974
First seen Apr 23, 2026 · Last updated May 15, 2026 · Updated 3 times
Summary
This study tests whether giving two targeted drugs (T-DM1 and pertuzumab) before surgery can completely eliminate cancer in women with early-stage HER2-positive breast cancer. About 164 participants with stage II or III disease will receive the combination, then have surgery to check if no cancer remains. The goal is to see if this approach works better for tumors with certain HER2 patterns.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Tennessee Oncology/Sarah Cannon Research Institute
Nashville, Tennessee, 37203, United States
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Vanderbilt-Ingram Cancer Center
Nashville, Tennessee, 37232, United States
Conditions
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