Engineered immune cells take aim at chest cancer
NCT ID NCT02414269
First seen Oct 31, 2025 · Last updated May 06, 2026 · Updated 21 times
Summary
This study tests a treatment using a patient's own immune cells (T cells) that are modified in a lab to attack cancer cells with a protein called mesothelin. It is for people with malignant pleural disease, including mesothelioma and cancers that have spread to the chest lining. The first part finds a safe dose, and the second part combines it with another drug (pembrolizumab) to see if it helps control the cancer.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Memorial Sloan Kettering Basking Ridge (Consent and Follow-Up)
Basking Ridge, New Jersey, United States
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Memorial Sloan Kettering Bergen (Consent and Follow-Up)
Montvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center (Consent and Follow-Up)
New York, New York, 10065, United States
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Memorial Sloan Kettering Commack (Consent and Follow-Up)
Commack, New York, United States
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Memorial Sloan Kettering Monmouth (Consent and Follow-Up)
Middletown, New Jersey, 07748, United States
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Memorial Sloan Kettering Westchester (Consent and Follow-Up)
Harrison, New York, 10604, United States
Conditions
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