New artificial disc aims to replace fusion for neck disc disease
NCT ID NCT05740176
First seen Jun 25, 2026 · Last updated Jul 07, 2026 · Updated 3 times
Summary
This study tests a new artificial disc called the Synergy Disc for people with two-level cervical degenerative disc disease (DDD) who haven't improved with non-surgical care. The disc is designed to replace damaged discs in the neck while preserving motion, unlike standard fusion surgery which locks the bones together. Researchers will compare the safety and effectiveness of the Synergy Disc to historical data from fusion patients, tracking outcomes like pain, function, and need for additional surgery over two years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Synergy Disc (artificial cervical disc)
- What this could lead to
- If successful, this could offer a motion-preserving alternative to spinal fusion for people with two-level cervical disc disease, potentially reducing the need for repeat surgeries.
- What could go wrong
- This is a non-randomized, historically controlled trial with 200 participants, so results may be less reliable than a randomized study. The device could fail, cause complications, or not prove superior to fusion.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Atlantic Brain and Spine
Reston, Virginia, 20190, United States
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Austin Neurosurgeons
Austin, Texas, 78746, United States
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Bone and Joint Clinic of Baton Rouge
Baton Rouge, Louisiana, 70808, United States
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Brain and Spine Center of South Florida
Delray Beach, Florida, 33445, United States
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Carolina NeuroSurgery and Spine Associates, PA
Charlotte, North Carolina, 28204, United States
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DFW Center for Spinal Disorders
Fort Worth, Texas, 76132, United States
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DOCS Health Management LLC
Los Angeles, California, 90048, United States
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HonorHealth
Scottsdale, Arizona, 85258, United States
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Indiana Spine Group
Carmel, Indiana, 46032, United States
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Institute of Neuro Innovation
Santa Monica, California, 91304, United States
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Kennedy-White Orthopaedic Center
Sarasota, Florida, 34232, United States
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Louisiana Spine Institute
Shreveport, Louisiana, 71101, United States
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M3 Emerging Medical Research
Durham, North Carolina, 27704, United States
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Michigan Orthopedic Surgeons
Royal Oak, Michigan, 48073, United States
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Oregon Spine Care
Tualatin, Oregon, 97062, United States
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Orthopedics Northeast
Fort Wayne, Indiana, 46825, United States
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Pinehurst Surgical Clinic
Pinehurst, North Carolina, 28374, United States
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Precision Spine and Orthopaedic Associates, PA
Overland Park, Kansas, 66211, United States
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Steamboat Orthopaedic and Spine Institute
Steamboat Springs, Colorado, 80487, United States
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Summit Spine
Portland, Oregon, 97225, United States
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Texas Spine Care Center
San Antonio, Texas, 78231, United States
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The Disc Replacement Center
West Jordan, Utah, 84088, United States
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Todd Lanman, MD
Beverly Hills, California, 90210, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a Two-Pronged surgical approach beat standard surgery for neck pain?
- New minimally invasive spine surgery could spare patients metal implants
- New screw cage may improve neck fusion surgery outcomes
- Artificial disc holds up over 5 years in neck pain study
- New artificial disc offers hope for chronic neck pain sufferers
- New artificial disc could replace fusion for neck pain