Could a daily capsule soothe your tummy troubles?

NCT ID NCT07420231

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether taking a combination of a prebiotic (berberine) and a postbiotic (inactivated Bifidobacterium longum) for 8 weeks can reduce belly pain and discomfort in adults. 140 people with ongoing gut issues will be randomly assigned to get the combo, one of the ingredients alone, or a placebo. The goal is to see if this synbiotic blend improves symptoms and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Berberine (prebiotic) and inactivated Bifidobacterium longum (postbiotic) taken as capsules
What this could lead to
If it works, this could offer a simple, natural way to reduce belly pain and bloating for people with ongoing gut discomfort.
What could go wrong
This is an early-stage trial with no phase, so results are uncertain. The effect may be small or no better than placebo, and supplements are not regulated like drugs.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Center of Investigation in Clinical Nutrition (CICN)

    RECRUITING

    Louvain-la-Neuve, Brabant Wallon, 1348, Belgium

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