Could a daily capsule soothe your tummy troubles?
NCT ID NCT07420231
First seen Feb 22, 2026 · Last updated Jun 23, 2026 · Updated 19 times
Summary
This study is testing whether taking a combination of a prebiotic (berberine) and a postbiotic (inactivated Bifidobacterium longum) for 8 weeks can reduce belly pain and discomfort in adults. 140 people with ongoing gut issues will be randomly assigned to get the combo, one of the ingredients alone, or a placebo. The goal is to see if this synbiotic blend improves symptoms and quality of life.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Center of Investigation in Clinical Nutrition (CICN)
RECRUITINGLouvain-la-Neuve, Brabant Wallon, 1348, Belgium
Contact Email: •••••@•••••
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Berberine (prebiotic) and inactivated Bifidobacterium longum (postbiotic) taken as capsules
What this could lead to
If it works, this could offer a simple, natural way to reduce belly pain and bloating for people with ongoing gut discomfort.
What could go wrong
This is an early-stage trial with no phase, so results are uncertain. The effect may be small or no better than placebo, and supplements are not regulated like drugs.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.