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Gut health boost: synbiotics show promise for diabetes management

NCT ID NCT04552002

Completed Disease control Sponsor: Imam Abdulrahman Bin Faisal University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether taking a synbiotic (a mix of probiotics and prebiotics) for 6 months could improve blood sugar control, reduce inflammation, and change body composition in adults with prediabetes or type 2 diabetes. Researchers recruited 64 participants from a hospital in Saudi Arabia and measured markers like HbA1c, inflammatory proteins, and body fat. The goal was to see if this simple dietary supplement could support diabetes management by targeting the gut microbiome.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
synbiotic (probiotics and prebiotics)
What this could lead to
If it works, this could point toward a simple dietary supplement to help manage blood sugar and inflammation in people with prediabetes or type 2 diabetes.
What could go wrong
This is a small, completed Phase 3 trial with only 64 participants, so results may not apply to everyone. Dietary supplements often show modest effects, and the study did not test long-term outcomes or safety beyond 6 months.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

prediabetes syndrome type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIETARY SUPPLEMENTS

Contacts and locations

Locations

  • Family Medicince Community Centre

    Dammam, Eastern Province, Saudi Arabia

  • King Fahd University Hospital

    Dammam, Eastern Province, Saudi Arabia

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