New video program aims to ease symptoms for young cancer patients

NCT ID NCT05593016

Completed Symptom relief Sponsor: Duke University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new program called SMILE that helps teens and young adults (ages 15-29) with advanced cancer manage symptoms like pain, fatigue, and emotional distress. The program includes four video sessions at home, teaching relaxation and coping skills. Researchers checked if the program was acceptable and practical for patients, with 75 participants including patients and caregivers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Symptom Management for Improved Physical and Emotional Wellbeing (SMILE) program
What this could lead to: If it works, this could provide a practical, home-based program to help young people with advanced cancer better manage pain, fatigue, and emotional distress.
What could go wrong: This is a small, early-stage study focused on feasibility, not effectiveness. The intervention may not prove helpful in larger trials or for all patients.

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Conditions

The condition(s) this trial relates to.

cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADOLESCENT AND YOUNG ADULT CANCER PATIENT

Contacts and locations

Locations

Duke Cancer Institute

Durham, North Carolina, 27701, United States

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