Eye drops could replace needles for wet AMD?

NCT ID NCT05637255

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested three different doses of SYL1801 eye drops in 99 people with wet age-related macular degeneration (AMD). The goal was to see if the drops are safe and can improve or maintain vision. Participants used the drops for a set period, and their vision was measured after 42 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SYL1801 eye drops

What this could lead to

If successful, SYL1801 could offer a non-invasive eye drop treatment for wet AMD, potentially reducing the need for frequent injections.

What could go wrong

This is a small, early-phase trial (Phase 2) with only 99 participants. The eye drops may not improve vision as hoped, and long-term safety is not yet established.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

macular degeneration wet macular degeneration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • SYL1801 Investigative Site

    Brno, 62500, Czechia

  • SYL1801 Investigative Site

    Chomutov, 43001, Czechia

  • SYL1801 Investigative Site

    Frýdek-Místek, 738 01, Czechia

  • SYL1801 Investigative Site

    Kyjov, 69701, Czechia

  • SYL1801 Investigative Site

    Liberec, 46063, Czechia

  • SYL1801 Investigative Site

    Ostrava, 70200, Czechia

  • SYL1801 Investigative Site

    Prague, 14000, Czechia

  • SYL1801 Investigative Site

    Prague, 17000, Czechia

  • SYL1801 Investigative Site

    Gdansk, 80-809, Poland

  • SYL1801 Investigative Site

    Krakow, 31-070, Poland

  • SYL1801 Investigative Site

    Rzeszów, 35-017, Poland

  • SYL1801 Investigative Site

    Warsaw, 01-258, Poland

  • SYL1801 Investigative Site

    Bratislava, 85107, Slovakia

  • SYL1801 Investigative Site

    Košice, 04011, Slovakia

  • SYL1801 Investigative Site

    Poprad, 05801, Slovakia

  • SYL1801 Investigative Site

    Žilina, Slovakia