New hope for HER2+ breast cancer: switching drug combos after treatment fails

NCT ID NCT07455188

First seen Mar 18, 2026 · Last updated Jun 16, 2026 · Updated 11 times

Summary

This study looks at what happens when people with HER2-positive advanced breast cancer switch between two different targeted therapy combinations after their first treatment stops working. About 600 women will be split into two groups: one switches from HP+chemo to HPy+chemo, the other does the opposite. The goal is to see which switch works better at controlling the cancer and helping people live longer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Zhejiang Cancer Hospital

    RECRUITING

    Zhejiang, Hangzhou, 310000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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Conditions inferred from the trial description

These were inferred from the trial's summary, not listed by the trial registrant.