New pill shows promise for rare lung cancer mutations

NCT ID NCT06010329

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing an oral drug called sutetinib maleate in people with advanced non-small cell lung cancer that has uncommon EGFR mutations. The goal is to see if the drug can shrink tumors and control the disease. About 66 adults will take the drug and be monitored for response and side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Sutetinib maleate (a targeted cancer drug taken orally)

What this could lead to

If successful, this could provide a new treatment option for people with non-small cell lung cancer that has uncommon EGFR mutations, potentially shrinking tumors and delaying progression.

What could go wrong

This is an early-phase (Phase 2) trial with only 66 participants, so results may not apply to everyone. The drug may cause side effects and may not work better than existing treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for NON-SMALL-CELL LUNG CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mission Cancer + Blood - Mission Cancer Foundation

    RECRUITING

    Des Moines, Iowa, 50309, United States

  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33612, United States

  • Northwell Health

    ACTIVE_NOT_RECRUITING

    New Hyde Park, New York, 11042, United States

  • Norton Cancer Institute - Downtown

    WITHDRAWN

    Louisville, Kentucky, 40202, United States

  • Oncology Physicians Network Healthcare

    WITHDRAWN

    Glendale, California, 91203, United States

  • Perlmutter Cancer Center - 34th Street

    RECRUITING

    New York, New York, 10016, United States

  • University Cancer & Blood Center (UCBC) - Athens

    RECRUITING

    Athens, Georgia, 30607, United States

  • University of California San Diego Moores Cancer Center

    RECRUITING

    La Jolla, California, 92093, United States

  • University of Texas MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States