New pill shows promise for rare lung cancer mutations
NCT ID NCT05168566
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new drug called sutetinib in people with advanced non-small cell lung cancer that has certain uncommon EGFR mutations (L861Q, G719X, or S768I). About 99 participants will take the drug by mouth to see if it shrinks tumors and how safe it is. The goal is to find a better treatment option for this specific group of patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Sutetinib maleate capsule
What this could lead to
If successful, this could provide a new targeted treatment option for people with non-small cell lung cancer that has certain uncommon EGFR mutations.
What could go wrong
This is an early-phase (2b) study with only 99 participants, so results may not apply broadly. The drug may not work as hoped or could cause side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Baptist Health
WITHDRAWNLouisville, Kentucky, 40223, United States
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Beijing Cancer Hospital
ACTIVE_NOT_RECRUITINGBeijing, Beijing Municipality, 100142, China
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Beijing Chest Hospital
ACTIVE_NOT_RECRUITINGBeijing, Beijing Municipality, 101125, China
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Cancer Hospital Chinese Academy of Medical Sciences
ACTIVE_NOT_RECRUITINGBeijing, Beijing Municipality, 100021, China
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FirstHealth Cancer Center
RECRUITINGPinehurst, North Carolina, 28374, United States
Contact
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Harbin Medical University Cancer Hospital
ACTIVE_NOT_RECRUITINGHarbin, Heilongjiang, 150086, China
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Henan Cancer Hospital
ACTIVE_NOT_RECRUITINGZhengzhou, Henan, 450003, China
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Hunan Cancer Hospital
ACTIVE_NOT_RECRUITINGChangsha, Hunan, 410006, China
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Jiangsu Province Hospital
ACTIVE_NOT_RECRUITINGNanjing, Jiangsu, 210029, China
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Jilin Cancer Hospital
ACTIVE_NOT_RECRUITINGChangchun, Jilin, 130012, China
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Linyi Cancer Hospital
ACTIVE_NOT_RECRUITINGLinyi, Shangdong, 276001, China
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OPN Healthcare, Inc.
RECRUITINGGlendale, California, 91203, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Peking Union Medical College Hospital
ACTIVE_NOT_RECRUITINGBeijing, Beijing Municipality, 100730, China
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Shanghai Chest Hospital
ACTIVE_NOT_RECRUITINGShanghai, Shanghai Municipality, 200052, China
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Shanghai Pulmonary Hospital
ACTIVE_NOT_RECRUITINGShanghai, Shanghai Municipality, 200437, China
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Sichuan Cancer Hospital
ACTIVE_NOT_RECRUITINGChengdu, Sichuan, 610044, China
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The Affiliated Cancer Hospital of Chongqin University
ACTIVE_NOT_RECRUITINGChongqing, Chongqing Municipality, 400044, China
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The First Affiliated Hospital of Bengbu Medical College
ACTIVE_NOT_RECRUITINGBengbu, Anhui, 230000, China
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The First Affiliated Hospital of China Medical University
ACTIVE_NOT_RECRUITINGShengyang, Liaoning, 830000, China
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The First Affiliated Hospital of Guangzhou Medical University
ACTIVE_NOT_RECRUITINGGuangzhou, Guangdong, 510230, China
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The First Affiliated Hospital of Zhengzhou University
ACTIVE_NOT_RECRUITINGZhengzhou, Henan, 450052, China
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University Cancer & Blood Center
RECRUITINGAthens, Georgia, 30607, United States
Contact
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University of Maryland Medical Center
RECRUITINGBaltimore, Maryland, 21201, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Texas MD Anderson Cancer Center
ACTIVE_NOT_RECRUITINGHouston, Texas, 77030, United States
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Wuhan Union Hospital of China
ACTIVE_NOT_RECRUITINGWuhan, Hubei, 430000, China
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Zhejiang Cancer Hospital
ACTIVE_NOT_RECRUITINGHangzhou, Zhejiang, 310022, China