New hope for Hard-to-Treat lymphoma: experimental drug surovatamig enters phase 2 trial

NCT ID NCT06526793

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 27 times

Summary

This study tests an experimental drug called surovatamig (AZD0486) in adults with B-cell non-Hodgkin lymphoma that has come back or stopped responding to at least two prior treatments. The goal is to see how well the drug shrinks tumors and to check for side effects. About 240 participants will receive the drug alone, without other cancer treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

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Locations

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Phoenix, Arizona, 85054, United States
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Duarte, California, 91010, United States
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Jacksonville, Florida, 32224, United States
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Tampa, Florida, 33612, United States
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Chicago, Illinois, 60637, United States
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Iowa City, Iowa, 52242, United States
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Waukee, Iowa, 50263, United States
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Overland Park, Kansas, 66204, United States
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Rochester, Minnesota, 55905, United States
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St Louis, Missouri, 63110, United States
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New Brunswick, New Jersey, 08901, United States
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New York, New York, 10016, United States
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Charlotte, North Carolina, 28204, United States
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Columbus, Ohio, 43210, United States
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Portland, Oregon, 97239, United States
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Philadelphia, Pennsylvania, 19104, United States
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Pittsburgh, Pennsylvania, 15232, United States
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Pittsburgh, Pennsylvania, 15232, United States
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Nashville, Tennessee, 37203, United States
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Austin, Texas, 78704, United States
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Houston, Texas, 77030, United States
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San Antonio, Texas, 78229, United States
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Milwaukee, Wisconsin, 53226, United States
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Heidelberg, 3084, Australia
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Kogarah, NSW 2217, Australia
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Macquarie University, 2109, Australia
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Nedlands, 6009, Australia
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SUSPENDED

Porto Alegre, 90035903, Brazil
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São Paulo, 01401-002, Brazil
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São Paulo, 05652-900, Brazil
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Barrie, Ontario, L4M 6M2, Canada
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Brampton, Ontario, L6R 3J7, Canada
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Ottawa, Ontario, K1H 8L6, Canada
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Toronto, Ontario, M5G 2M9, Canada
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Chengdu, 610041, China
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Chengdu, 610072, China
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Guangzhou, 510060, China
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Nanchang, 330029, China
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Nanjing, 210029, China
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Nantong, 226001, China
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Shandong, China
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Shanghai, 200025, China
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Shanghai, 200032, China
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Tianjin, 300020, China
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Zhengzhou, 450008, China
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Aalborg, 9100, Denmark
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Copenhagen, 2100, Denmark
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Vejle, 7100, Denmark
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Montpellier, 34295, France
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Paris, 75010, France
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Pierre-Bénite, 69495, France
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Rouen, 76038, France
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Berlin, 10967, Germany
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Chemnitz, 9116, Germany
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Essen, 45147, Germany
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Jena, 07747, Germany
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Würzburg, 97080, Germany
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Hong Kong, 999077, Hong Kong
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Shatin, 00000, Hong Kong
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Alessandria, 15121, Italy
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Bologna, 40138, Italy
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Busto Arsizio, 21052, Italy
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Milan, 20132, Italy
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Milan, 20141, Italy
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Roma, 161, Italy
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Chiba, 260-8717, Japan
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Kashiwa, 277-8577, Japan
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Kōtoku, 135-8550, Japan
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Kumamoto, 860-0008, Japan
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Niigata, 951-8520, Japan
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Okayama, 700-8558, Japan
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Osaka, 541-8567, Japan
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Yokohama, 241-8515, Japan
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Seoul, 03080, South Korea
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Seoul, 06351, South Korea
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Seoul, 06591, South Korea
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Seoul, 3722, South Korea
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Seoul, 5505, South Korea
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Barcelona, 08035, Spain
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Madrid, 28040, Spain
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Pozuelo de Alarcón, 28223, Spain
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Gothenburg, 41345, Sweden
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Stockholm, 17176, Sweden
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Kaohsiung City, 80756, Taiwan
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Kaohsiung City, 833401, Taiwan
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Taichung, 404, Taiwan
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Taichung, 40705, Taiwan
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Tainan, 70403, Taiwan
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Taipei, 106, Taiwan
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London, SE5 9RS, United Kingdom
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Manchester, M20 4BX, United Kingdom
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Norwich, NR4 7UY, United Kingdom
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Nottingham, NG5 1PB, United Kingdom
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Plymouth, PL6 8DH, United Kingdom

Conditions

Explore the condition pages connected to this study.

B-CELL NON HODGKIN LYMPHOMA B-CELL NON-HODGKIN LYMPHOMA FOLLICULAR LYMPHOMA ( FL) LARGE B-CELL LYMPHOMA (LBCL) LARGE B-CELL LYMPHOMA (LBCL)