LARGE B-CELL LYMPHOMA (LBCL)
Clinical trials for LARGE B-CELL LYMPHOMA (LBCL) explained in plain language.
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New hope for elderly lymphoma patients: drug combo targets cancer without harsh chemo
Disease control Recruiting nowThis study tests a combination of four drugs (Pola-ZR-Glo) in 30 older adults (70+) with untreated large B-cell lymphoma who cannot tolerate standard chemotherapy. The goal is to control the disease and improve survival while monitoring side effects and quality of life. Participa…
Matched conditions: LARGE B-CELL LYMPHOMA (LBCL)
Phase: PHASE2 • Sponsor: Ruijin Hospital • Aim: Disease control
Last updated May 17, 2026 06:48 UTC
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Immune cell therapy shows promise for aggressive blood cancer
Disease control Recruiting nowThis study tests a treatment called CD19 CAR-T therapy for people newly diagnosed with a fast-growing type of blood cancer called high-risk large B-cell lymphoma. The therapy uses a patient's own immune cells, which are modified in a lab to better find and kill cancer cells. The …
Matched conditions: LARGE B-CELL LYMPHOMA (LBCL)
Phase: PHASE2 • Sponsor: Zhejiang University • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New hope for hard-to-treat blood cancers: experimental drug enters phase 2 trial
Disease control Recruiting nowThis study tests a new drug called surovatamig in 240 adults with a type of blood cancer (B-cell non-Hodgkin lymphoma) that has returned or not improved after at least two prior treatments. The drug is given alone to see if it can shrink tumors and how safe it is. The trial is op…
Matched conditions: LARGE B-CELL LYMPHOMA (LBCL)
Phase: PHASE2 • Sponsor: AstraZeneca • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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Cheaper CAR-T therapy could expand access for lymphoma patients
Disease control Recruiting nowThis study tests a lower-cost, academic version of CAR-T cell therapy for adults with relapsed or refractory large B-cell lymphoma. The treatment uses the patient's own immune cells, modified to target cancer cells. The goal is to see if this more affordable approach is safe and …
Matched conditions: LARGE B-CELL LYMPHOMA (LBCL)
Sponsor: N.N. Alexandrov National Cancer Centre • Aim: Disease control
Last updated May 06, 2026 16:01 UTC
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New drug combo aims to boost CAR-T cell power against lymphoma
Disease control Recruiting nowThis early-stage study tests whether adding a drug called CLS-015 to standard CAR-T cell therapy can improve outcomes for people with large B-cell lymphoma that has stopped responding or is progressing. The drug is designed to reverse immune-suppressing effects in the tumor envir…
Matched conditions: LARGE B-CELL LYMPHOMA (LBCL)
Phase: PHASE1 • Sponsor: Tel-Aviv Sourasky Medical Center • Aim: Disease control
Last updated May 05, 2026 11:55 UTC