New immunotherapy combo may let older colon cancer patients skip surgery

NCT ID NCT06205836

First seen Dec 12, 2025 · Last updated May 22, 2026 · Updated 23 times

Summary

This study tests whether two immunotherapy drugs, cemiplimab alone or combined with fianlimab, can eliminate tumors in older adults (age 70+) or those unfit for surgery with a specific genetic type of colorectal cancer (MSI-H). The goal is to achieve a complete response, meaning no cancer is found on scans or after surgery, allowing patients to avoid or delay surgery. The trial enrolls 44 participants and monitors them for 24 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins SKCCC

    RECRUITING

    Baltimore, Maryland, 21231, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.