New drug combo could spare seniors from colorectal cancer surgery

NCT ID NCT06205836

First seen Dec 12, 2025 · Last updated May 15, 2026 · Updated 22 times

Summary

This study tests whether two immunotherapy drugs, cemiplimab and fianlimab, can eliminate tumors in older patients (70+) or those unfit for surgery with a specific genetic type of colorectal cancer (MSI-H). Participants receive the drugs and are monitored with scans and scopes to see if the cancer disappears without needing an operation. The goal is to find a safer, effective alternative to surgery for this vulnerable group.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins SKCCC

    RECRUITING

    Baltimore, Maryland, 21231, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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