New trial aims to halve deaths in newborns with severe heart disease

NCT ID NCT07363538

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares performing heart surgery on newborns with complex congenital heart disease either before or after 7 days of age. Researchers will track which timing leads to fewer deaths and better recovery. The trial involves 738 babies across multiple hospitals in China.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

surgical operation

What this could lead to

If successful, this could establish the best timing for life-saving heart surgery in newborns, potentially halving death and non-recovery rates.

What could go wrong

This is a large trial but still early in its evaluation. The optimal timing may vary by individual, and results may not apply to all hospitals or countries.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for COARCTATION OF THE AORTA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

aorta coarctation congenital heart disease congenital total pulmonary venous return anomaly conotruncal heart malformations pulmonary atresia-intact ventricular septum syndrome pulmonic stenosis transposition of the great arteries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Central China Fuwai Hospital of Zhengzhou University

    RECRUITING

    Zhengzhou, Henan, 450000, China

  • Children's Hospital Affiliated to Nanjing Medical University

    NOT_YET_RECRUITING

    Nanjing, Jiangsu, 210008, China

  • Children's Hospital Zhejiang University School of Medicine

    NOT_YET_RECRUITING

    Hangzhou, Zhejiang, China

  • Children's Hospital of Chongqing Medical University

    NOT_YET_RECRUITING

    Chongqing, Chongqing Municipality, China

  • Fuwai Hospital, Chinese Academy of Medical Sciences

    RECRUITING

    Beijing, Beijing Municipality, 100037, China

  • Guangzhou Women and Children's Medical Center, Guangzhou Medical University

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, China

  • Qingdao Women and Children's Hospital

    NOT_YET_RECRUITING

    Qingdao, Shandong, 266000, China

  • Shanghai Children's Medical Center (SCMC) Affiliated to Shanghai Jiao Tong University School of Medicine

    NOT_YET_RECRUITING

    Shanghai, Shanghai Municipality, China

  • The First Affiliated Hospital of Air Force Medical University (Xijing Hospital)

    NOT_YET_RECRUITING

    Xi’an, Shanxi, China

  • The Second Xiangya Hospital of Central South University

    NOT_YET_RECRUITING

    Changsha, Hunan, China

  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

    NOT_YET_RECRUITING

    Wuhan, Hubei, China

  • West China Second Hospital of Sichuan University

    NOT_YET_RECRUITING

    Chengdu, Sichuan, China