Double attack: surgery plus laser zaps deadly brain tumors

NCT ID NCT07384884

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a new approach for a rare and aggressive brain tumor called butterfly glioblastoma, which crosses both sides of the brain and has a very poor outlook. The treatment combines open surgery to remove as much tumor as possible from one side, followed by a minimally invasive laser therapy to destroy the remaining tumor on the other side. The goal is to improve survival and preserve brain function, with 12 participants being closely monitored for cognitive and quality-of-life outcomes.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
surgery and laser interstitial thermal therapy (LITT)
What this could lead to
If successful, this combined approach could offer a new treatment option for patients with butterfly glioblastoma, potentially extending survival and reducing brain damage compared to current methods.
What could go wrong
This is a very early, small trial with only 12 participants, so results may not apply to all patients. The procedure carries risks like infection, bleeding, or stroke, and the tumor may still progress.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • King's College NHS Foundation Trust

    London, SE5 9RS, United Kingdom

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Other studies related to the condition(s) this trial covers.