Can surgery beat pancreatic cancer spread? new trial aims to find out

NCT ID NCT07340151

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial tests whether removing both the main pancreatic tumor and small spots in the liver or lungs after chemotherapy can help patients. It includes 40 people whose cancer has spread to only a few spots. Everyone gets the same treatment: chemo first, then surgery if the cancer shrinks or stays stable. The goal is to see if this approach is safe and effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
NALIRIFOX chemotherapy (liposomal irinotecan, oxaliplatin, 5-fluorouracil, folinic acid) followed by surgery
What this could lead to
If successful, this could show that removing both the main tumor and limited liver or lung spots after chemotherapy improves survival for some pancreatic cancer patients.
What could go wrong
This is a small, early-phase trial with only 40 people and no comparison group. The cancer may still return, and surgery carries risks like infection or complications.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The University of Texas Health Science Center San Antonio

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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