Poop pills from superdonors could tame colitis

NCT ID NCT05739864

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether fecal transplants from carefully selected 'superdonors' can help people with mild-to-moderate ulcerative colitis achieve remission. 42 adults with a recent diagnosis will receive either superdonor FMT or a placebo via colonoscopy and capsules. The main goal is to see if more patients are symptom-free 8 weeks after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

fecal microbiota transplantation (FMT) from superdonors

What this could lead to

If it works, this could offer a new, natural treatment option for ulcerative colitis that helps more patients achieve remission without strong drugs.

What could go wrong

This is an early phase 1/2 trial with only 42 people, so results may not apply to everyone. FMT carries risks like infection or worsening symptoms, and the superdonor approach is still unproven for colitis.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Gianluca Ianiro

    RECRUITING

    Rome, Lazio, 00168, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••