Poop pills from superdonors could tame colitis
NCT ID NCT05739864
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether fecal transplants from carefully selected 'superdonors' can help people with mild-to-moderate ulcerative colitis achieve remission. 42 adults with a recent diagnosis will receive either superdonor FMT or a placebo via colonoscopy and capsules. The main goal is to see if more patients are symptom-free 8 weeks after treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- fecal microbiota transplantation (FMT) from superdonors
- What this could lead to
- If it works, this could offer a new, natural treatment option for ulcerative colitis that helps more patients achieve remission without strong drugs.
- What could go wrong
- This is an early phase 1/2 trial with only 42 people, so results may not apply to everyone. FMT carries risks like infection or worsening symptoms, and the superdonor approach is still unproven for colitis.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Gianluca Ianiro
RECRUITINGRome, Lazio, 00168, Italy
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