Could a broccoli sprout compound protect aging hearts?

NCT ID NCT05408559

Terminated Disease control Sponsor: Texas Tech University Health Sciences Center Source: ClinicalTrials.gov ↗

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This study tests whether a supplement called sulforaphane, found in broccoli sprouts, can help prevent age-related declines in heart function. Researchers will give the supplement or a placebo to adults over 60 with a type of heart failure called HFpEF. They will measure heart function, exercise ability, and muscle strength before and after 24 weeks of treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: sulforaphane (broccoli sprout extract)
What this could lead to: If it works, this could point toward a simple dietary supplement to help protect heart function in older adults.
What could go wrong: This is an early-phase trial with a small number of participants, so results may not apply broadly. The supplement may not improve heart function or exercise capacity as hoped.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

diastolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIASTOLIC DYSFUNCTION DIASTOLIC HEART FAILURE SYSTOLIC DYSFUNCTION

Contacts and locations

Locations

Texas Tech University Health Sciences Center (TTUHSC)

Lubbock, Texas, 79430, United States

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