Spinal stimulation without tingling: a new hope for failed back surgery pain?

NCT ID NCT05169047

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a type of spinal cord stimulation that uses low-level electrical pulses (below the sensation threshold) against the best available medical treatments for people with ongoing back and leg pain after back surgery. About 114 participants will be randomly assigned to one of the two approaches. The goal is to see if this stimulation method leads to better overall well-being, pain relief, and function after six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

subthreshold spinal cord stimulation

What this could lead to

If successful, this could provide a non-drug option for managing chronic back and leg pain after failed back surgery, potentially reducing pain and improving quality of life.

What could go wrong

This is a relatively small, early-stage trial with no phase designation. The treatment may not prove more effective than standard medical care, and spinal cord stimulation carries risks like infection or device malfunction.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

complex regional pain syndrome type 2 Failed Back Surgery Syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AZ Delta

    Roeselare, Belgium

  • AZ Turnhout

    Turnhout, Belgium

  • Emmaüs, AZ Sint-Maarten

    Mechelen, Belgium

  • Jessa Ziekenhuis

    Hasselt, Belgium

  • Universitair Ziekenhuis Brussel

    Jette, 1090, Belgium