New pill aims to stop nausea and vomiting from popular Weight-Loss drugs

NCT ID NCT06500429

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 29 times

Summary

This study tested an experimental oral drug called NG101 to see if it could reduce stomach-related side effects (like nausea and vomiting) caused by GLP-1 agonist weight-loss injections such as semaglutide. 120 healthy adults with a BMI between 22 and 35 took either NG101 or a placebo for five days, and received a single dose of semaglutide on day two. Researchers tracked how long and how severe any stomach side effects lasted.

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Contacts and locations

Locations

  • Celerion

    Tempe, Arizona, 85283, United States

Conditions

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