Radioactive drug shows promise in early brain cancer trial

NCT ID NCT05109728

First seen Oct 01, 2025 · Last updated Apr 28, 2026 · Updated 20 times

Summary

This early-stage study tests a radioactive drug called [177Lu]Lu-DOTA-TATE in people with glioblastoma, an aggressive brain cancer. For newly diagnosed patients, the drug is given alongside standard radiation and chemotherapy. For those whose cancer has returned, it is given alone. The main goal is to find the safest dose and understand side effects. About 65 adults will take part.

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Contacts and locations

Locations

  • Col Uni Med Center New York Presby

    New York, New York, 10032, United States

  • MD Anderson Cancer Center Uni of Te

    Houston, Texas, 77030, United States

  • Novartis Investigative Site

    Bron, 69677, France

  • Novartis Investigative Site

    Marseille, 13885, France

  • Novartis Investigative Site

    Porto, 4200-072, Portugal

  • Novartis Investigative Site

    Granada, Andalusia, 18014, Spain

  • Novartis Investigative Site

    Barcelona, 08035, Spain

  • Novartis Investigative Site

    Barcelona, 08036, Spain

  • Novartis Investigative Site

    Madrid, 28041, Spain

  • Novartis Investigative Site

    Madrid, 28050, Spain

  • Novartis Investigative Site

    Lausanne, 1011, Switzerland

  • Novartis Investigative Site

    Zurich, 8091, Switzerland

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15213, United States

  • University of Wisconsin School of Medicine and Public Health

    Madison, Wisconsin, 53792-1615, United States

Conditions

Explore the condition pages connected to this study.