Could a common painkiller boost emergency contraception for obese women?
NCT ID NCT06306131
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This study investigates whether taking levonorgestrel (the active ingredient in Plan B One-Step) together with meloxicam (an anti-inflammatory drug) can delay ovulation by at least 7 days in women with obesity. Participants take placebo in one menstrual cycle and the drug combination in the next, with daily urine tests and ultrasounds to track ovulation. The goal is to see if this combination works better than placebo for emergency contraception in this population.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
levonorgestrel and meloxicam
What this could lead to
If successful, this could lead to a more effective emergency contraceptive option for women with obesity.
What could go wrong
This is a very small early-phase study with only 4 participants, so results may not apply broadly. The combination may cause side effects like unscheduled bleeding.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Carolina Women's Research and Wellness Center
Raleigh, North Carolina, 27713, United States