Could a common painkiller boost emergency contraception for obese women?
NCT ID NCT06306131
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This study investigates whether taking levonorgestrel (the active ingredient in Plan B One-Step) together with meloxicam (an anti-inflammatory drug) can delay ovulation by at least 7 days in women with obesity. Participants take placebo in one menstrual cycle and the drug combination in the next, with daily urine tests and ultrasounds to track ovulation. The goal is to see if this combination works better than placebo for emergency contraception in this population.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- levonorgestrel and meloxicam
- What this could lead to
- If successful, this could lead to a more effective emergency contraceptive option for women with obesity.
- What could go wrong
- This is a very small early-phase study with only 4 participants, so results may not apply broadly. The combination may cause side effects like unscheduled bleeding.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Carolina Women's Research and Wellness Center
Raleigh, North Carolina, 27713, United States
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