Could a hormone plus painkiller boost emergency contraception?
NCT ID NCT05695352
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed phase 2 study tested whether taking levonorgestrel (the hormone in Plan B) plus meloxicam (an anti-inflammatory) can delay ovulation by 7 days in healthy women. Nineteen women aged 18-40 took either placebo or the drug combo around ovulation. The goal was to see if the combo could give a longer window to prevent pregnancy. Results are pending.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Levonorgestrel (a hormone) and meloxicam (an anti-inflammatory drug)
- What this could lead to
- If it works, this could lead to a more effective emergency contraceptive that delays ovulation longer than current options.
- What could go wrong
- This is a small, early-phase study with only 19 participants, so results may not apply to everyone. Side effects like nausea or cramping are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Carolina Women's Research and Wellness Center
Raleigh, North Carolina, 27713, United States
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