Can a Mega-Dose of statin help stroke patients? safety trial completed

NCT ID NCT01976936

First seen Dec 12, 2025 · Last updated May 16, 2026 · Updated 23 times

Summary

This study tested whether a very high dose of lovastatin (a common cholesterol drug) is safe for people who recently had an ischemic stroke. 162 participants received either the high-dose lovastatin or a placebo within 24 hours of their stroke. The main goal was to check for liver or muscle damage, with follow-up over 3 months.

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Contacts and locations

Locations

  • Brigham & Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Emory University

    Atlanta, Georgia, 30322, United States

  • Jackson Memorial Hospital

    Miami, Florida, 33136, United States

  • Mount Sinai School of Medicine

    New York, New York, 10029, United States

  • The Hospital of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of California, Los Angeles Stroke Network

    Los Angeles, California, 90024, United States

  • University of Miami Miller School of Medicine

    Miami, Florida, 33136, United States

Conditions

Explore the condition pages connected to this study.