Stroke drug boost: could tenecteplase finish the job?

NCT ID NCT07471282

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving a clot-busting drug called tenecteplase directly into the brain artery can help stroke patients who still have blocked blood flow after a standard clot removal procedure. About 344 adults with a major stroke will be randomly assigned to receive either the drug or a placebo. The goal is to see if the drug improves recovery and reduces disability at 90 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Tenecteplase (a clot-busting drug)

What this could lead to

If it works, this could provide a better way to restore blood flow and improve recovery for stroke patients whose arteries aren't fully cleared by the standard procedure.

What could go wrong

This is a Phase 3 trial, but it's still early to know if the drug will be effective or safe. There is a risk of bleeding in the brain, and the results may not apply to all stroke types.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cerebral artery occlusion large artery stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The First Affiliated Hospital of China Medical University

    Shenyang, Liaoning, 110000, China