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Light and electrical pulses: a new combo to rewire the brain after stroke?

NCT ID NCT07807176

Disease control Sponsor: Chang Gung Memorial Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 08, 2026 · Last updated Sep 09, 2026 · Updated 1 time

Summary

This study tests whether combining non-invasive light therapy on the head, electrical stimulation cycling for the arms, and cognitive tasks can improve thinking and arm movement in adults who have had a stroke. Participants attend 10 sessions over 2 weeks, and researchers measure changes in attention, memory, and upper-limb function before, right after, and 3 months later. The goal is to find a rehab approach that helps the brain and body recover together.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Functional electrical stimulation cycling, cognitive task training, and photobiomodulation (light therapy) applied to the ear or forehead
What this could lead to
If it works, this could point toward a more effective rehabilitation approach that improves both thinking and arm movement after a stroke.
What could go wrong
This is an early exploratory trial, so the combined therapy may not prove more effective than standard rehab. Light therapy and electrical stimulation are generally safe, but some people may find the sessions tiring or uncomfortable.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 150 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Oct 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 20 to 80 years. * First-ever ischemic or hemorrhagic stroke with unilateral impairment in hand or arm strength or motor function. * Medically stable and able to participate safely in the training program. * Able to understand the study procedures and sign the informed consent form. * Able to follow verbal instructions, comply with study procedures, and complete all assessments. * Able to maintain a seated position and participate in each training session (approximately 40-60 minutes). Exclusion Criteria: * Stroke involving the brainstem or cerebellum. * History of epilepsy, photosensitive epilepsy, or a tendency to faint. * Presence of implanted electronic devices, such as pacemakers, implantable cardioverter-defibrillators (ICD), or other electronic medical implants (e.g., artificial heart, infusion pumps, cochlear implants). * Wounds, infections, or significant skin problems at potential stimulation sites (ear or scalp). * Presence of major psychiatric disorders or inability to understand or cooperate with testing. * Cardiovascular or vascular-related conditions, including severe heart disease, uncontrolled arrhythmia, or medical advice against exercise; use of anticoagulant medication that makes laser stimulation inappropriate. * Acute illness, such as fever or active infection. * Botulinum toxin injections or relevant surgeries within the past six months. * Photosensitive disorders (e.g., lupus, porphyria) or current use of photosensitizing medications. * Inability to safely perform cycling training (e.g., recent fractures, severe spasticity, difficulty maintaining seated posture). * Pregnant or breastfeeding individuals. * Any other condition deemed unsuitable by the study physician (e.g., severe claustrophobia).

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Conditions

The condition(s) this trial relates to.

stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stroke

How to take part

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  1. The official record

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