Major stroke prevention trial tests new drugs against standard care

NCT ID NCT05047172

Ongoing Disease control Sponsor: University of Florida Source: ClinicalTrials.gov ↗

Summary

This large study aims to find the best medication to prevent future strokes in people who have recently had a stroke caused by a severely narrowed brain artery. It will compare newer blood-thinning drugs (rivaroxaban and ticagrelor) to the standard drug (clopidogrel) in over 1,600 participants. The main goal is to see which treatment is most effective at preventing another stroke, brain bleed, or death from vascular causes within one year.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Abbott Northwestern Hospital

Minneapolis, Minnesota, 55407, United States
Advocate Christ Medical Center

Oak Lawn, Illinois, 60453, United States
Augusta University Medical Center

Augusta, Georgia, 30912, United States
Baptist Health Lexington

Lexington, Kentucky, 40503, United States
Baptist Medical Center Jacksonville

Jacksonville, Florida, 32207, United States
Barnes Jewish Hospital

St Louis, Missouri, 62269, United States
Beth Israel Deaconess Medical Center

Boston, Massachusetts, 02215, United States
Boston Medical Center

Boston, Massachusetts, 02118, United States
Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States
Broward Health Medical Center

Fort Lauderdale, Florida, 33316, United States
Buffalo General Medical Center

Buffalo, New York, 14202, United States
Carilion Roanoke Memorial Hospital

Roanoke, Virginia, 24011, United States
Carolinas Medical Center

Charlotte, North Carolina, 28207, United States
Cleveland Clinic

Cleveland, Ohio, 44195, United States
Cleveland Clinic Akron General

Akron, Ohio, 44307, United States
Cleveland Clinic Tradition Hospital

Port Saint Lucie, Florida, 34987, United States
Cooper University Hospital

Camden, New Jersey, 08103, United States
Covenant Medical Center

Lubbock, Texas, 79410, United States
Duke University Hospital

Durham, North Carolina, 27710, United States
ECU Health Medical Center

Greenville, North Carolina, 27834, United States
Emory University Hospital

Atlanta, Georgia, 30303, United States
Endeavor Health Edward Hospital

Naperville, Illinois, 60540, United States
Evanston Hospital

Evanston, Illinois, 60201, United States
Good Samaritan Hospital

Cincinnati, Ohio, 45220, United States
Grady Memorial Hospital

Atlanta, Georgia, 30303, United States
Harborview Medical Center

Seattle, Washington, 98104, United States
Hartford Hospital

Hartford, Connecticut, 06102, United States
Henry Ford Hospital

Detroit, Michigan, 48202, United States
Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States
Houston Methodist Hospital

Houston, Texas, 77030, United States
Inova Fairfax Hospital

Falls Church, Virginia, 22042, United States
Jackson Memorial Hospital

Miami, Florida, 33136, United States
Javon Bea Hospital - Riverside

Rockford, Illinois, 61114, United States
Jefferson Abington Hospital

Abington, Pennsylvania, 19001, United States
Jersey Shore University Medical Center

Neptune City, New Jersey, 07753, United States
Kaiser Permanente Fontana Medical Center

Fontana, California, 92335, United States
Kaiser Permanente Los Angeles Medical Center

Los Angeles, California, 90027, United States
Kings County Hospital Center

Brooklyn, New York, 11203, United States
Long Beach Memorial Medical Center

Long Beach, California, 90806, United States
Los Alamitos Medical Center

Los Alamitos, California, 90720, United States
M Health Fairview Southdale Hospital

Edina, Minnesota, 55414, United States
M Health Fairview University of Minnesota Medical Center

Minneapolis, Minnesota, 55415, United States
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
Mayo Clinic

Phoenix, Arizona, 85054, United States
Mayo Clinic

Jacksonville, Florida, 32224, United States
McLaren Flint

Flint, Michigan, 48532, United States
McLaren Macomb

Mount Clemens, Michigan, 48043, United States
MedStar Washington Hospital Center

Washington D.C., District of Columbia, 20010, United States
Medical City Plano

Plano, Texas, 75075, United States
Medical University of South Carolina University Hospital

Charleston, South Carolina, 29425, United States
Memorial Hermann Texas Medical Center

Houston, Texas, 77030, United States
Memorial Hospital of Carbondale

Carbondale, Illinois, 62901, United States
Mercy San Juan Medical Center

Carmichael, California, 95608, United States
Mercy St. Vincent Medical Center

Toledo, Ohio, 43608, United States
Methodist University Hospital

Memphis, Tennessee, 38104, United States
Metro Health Hospital

Wyoming, Michigan, 49519, United States
Montefiore Medical Center

The Bronx, New York, 10467, United States
Morton Plant Hospital

Clearwater, Florida, 33756, United States
Moses H. Cone Memorial Hospital

Greensboro, North Carolina, 27405, United States
NYP Columbia University Medical Center

New York, New York, 10032, United States
NYP Weill Cornell Medical Center

New York, New York, 10021, United States
NYU Langone Hospital - Brooklyn

Brooklyn, New York, 11220, United States
North Shore University Hospital

Lake Success, New York, 11042, United States
OSU Wexner Medical Center

Columbus, Ohio, 43210, United States
OU Medical Center

Oklahoma City, Oklahoma, 73104, United States
Ochsner Medical Center - Main Campus

New Orleans, Louisiana, 70121, United States
Oregon Health & Science University Hospital

Portland, Oregon, 97239, United States
Prisma Health Greenville Memorial Hospital

Greenville, South Carolina, 29605, United States
Prisma Health Richland Hospital

Columbia, South Carolina, 29203, United States
Providence Little Company of Mary Medical Center Torrance

Torrance, California, 90503, United States
Providence St. Vincent Medical Center

Portland, Oregon, 97225, United States
Rhode Island Hospital

Providence, Rhode Island, 02903, United States
Ronald Reagan UCLA Medical Center, Los Angeles, CA

Los Angeles, California, 90095, United States
Rush University Medical Center

Chicago, Illinois, 60612, United States
SUNY Downstate Medical Center

Brooklyn, New York, 11203, United States
Salinas Valley Memorial Hospital

Salinas, California, 93901, United States
St. Joseph's Hospital and Medical Center

Phoenix, Arizona, 85013, United States
St. Mary's Medical Center

Grand Junction, Colorado, 81501, United States
Strong Memorial Hospital

Rochester, New York, 14642, United States
Swedish Medical Center - Cherry Hill Campus

Seattle, Washington, 98122, United States
Tampa General Hospital

Tampa, Florida, 33606, United States
Temple University Hospital, Philadelphia

Philadelphia, Pennsylvania, 19140, United States
The Mount Sinai Hospital

New York, New York, 10029, United States
The Neuron Clinic - Chula Vista

Chula Vista, California, 91910, United States
The University of Vermont Medical Center

Burlington, Vermont, 05401, United States
Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, 19107, United States
Toledo Hospital

Toledo, Ohio, 43606, United States
UC Davis Medical Center

Sacramento, California, 95817, United States
UC Irvine Medical Center

Orange, California, 92868, United States
UCSD Medical Center - Hillcrest Hospital

San Diego, California, 92103, United States
UF Health Shands Hospital

Gainesville, Florida, 32608, United States
UH Cleveland Medical Center

Cleveland, Ohio, 44106, United States
UMass Memorial Medical Center

Worcester, Massachusetts, 01655, United States
UPMC Altoona

Altoona, Pennsylvania, 16601, United States
UPMC Hamot

Erie, Pennsylvania, 16550, United States
UPMC Presbyterian Hospital

Pittsburgh, Pennsylvania, 15213, United States
UT Health Tyler

Tyler, Texas, 75708, United States
UVA Medical Center

Charlottesville, Virginia, 22903, United States
University of Alabama Hospital

Birmingham, Alabama, 35233, United States
University of Chicago Medical Center

Chicago, Illinois, 60637, United States
University of Cincinnati Medical Center

Cincinnati, Ohio, 45267, United States
University of Colorado Hospital

Aurora, Colorado, 80045, United States
University of Illinois Hospital

Chicago, Illinois, 60612, United States
University of Kansas Hospital

Kansas City, Kansas, 66160, United States
University of Kentucky Hospital

Lexington, Kentucky, 40536, United States
University of Maryland Medical Center

Baltimore, Maryland, 21201, United States
University of Mississippi Medical Center

Jackson, Mississippi, 39216, United States
University of Missouri Health Care

Columbia, Missouri, 65212, United States
University of Nebraska Medical Center

Omaha, Nebraska, 68198, United States
University of New Mexico Hospital

Albuquerque, New Mexico, 87106, United States
University of South Alabama University Hospital

Mobile, Alabama, 36604, United States
University of Texas Health Science Center San Antonio

San Antonio, Texas, 78229, United States
University of Texas Medical Branch

Galveston, Texas, 77555, United States
University of Wisconsin University Hospital

Madison, Wisconsin, 53792, United States
Valley Hospital

Ridgewood, New Jersey, 07450, United States
Wake Forest Baptist Medical Center

Winston-Salem, North Carolina, 27157, United States
Yale New Haven Hospital

New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.

INTRACRANIAL ARTERIOSCLEROSIS STROKE