Lupus drug withdrawal trial aims to save eyesight in seniors

NCT ID NCT05799378

First seen Mar 10, 2026 · Last updated Jun 15, 2026 · Updated 14 times

Summary

This study tests whether people aged 60 and older with stable lupus can safely stop taking hydroxychloroquine, a drug that can damage the eyes over time. Half of the 330 participants will switch to a placebo, while the other half stays on the drug. Researchers will monitor for lupus flare-ups and eye health over one year to see if stopping is safe.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Columbia University Irving Medical Center/New York Presbyterian

    RECRUITING

    New York, New York, 10032, United States

  • Hackensack Meridian Health

    RECRUITING

    Hackensack, New Jersey, 07601, United States

  • Hospital for Special Surgery

    RECRUITING

    New York, New York, 10021, United States

  • Montefiore Medical Center/Albert Einstein College of Medicine

    RECRUITING

    The Bronx, New York, 10461, United States

  • NYC Health + Hospitals/Bellevue

    RECRUITING

    New York, New York, 10016, United States

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

  • Oklahoma Medical Research Foundation

    RECRUITING

    Oklahoma City, Oklahoma, 73104, United States

  • Penn State MS Hershey Medical Center

    RECRUITING

    Hershey, Pennsylvania, 17033, United States

  • University of California, Los Angeles

    RECRUITING

    Los Angeles, California, 90095, United States

  • VA NY Harbor Healthcare System

    RECRUITING

    New York, New York, 10010, United States

Conditions

Explore the condition pages connected to this study.