Hepatitis b patients may be able to ditch daily pills, new trial hopes
NCT ID NCT04782375
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adults with chronic hepatitis B who have no liver scarring can safely stop taking antiviral drugs. The 140 participants have undetectable virus levels and negative HBeAg status. Researchers will monitor for viral relapse and liver problems over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
discontinuation of antiviral treatment
What this could lead to
If successful, this could show that some patients with chronic hepatitis B can safely stop long-term antiviral therapy without the virus coming back.
What could go wrong
This is a small, early-phase trial without a control group, so results may not apply widely. There is a risk of viral relapse or liver problems after stopping medication.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Asan Medical Center
Seoul, South Korea
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Chung-Ang University Hospital
Seoul, South Korea
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Konkuk University Hospital
Seoul, South Korea
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Korea University Guro Hospital
Seoul, South Korea
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Kyung-Hee University Hospital
Seoul, South Korea
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Kyungpook National University Hospital
Daegu, South Korea
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Samsung Medical center
Seoul, South Korea
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Seoul National University Hospital
Seoul, South Korea
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Ulsan University Hospital
Ulsan, South Korea